Publicaciones

Un interruptor de afuera hacia adentro en la señalización de integrina causado por señales químicas y mecánicas en astrocitos reactivos

Autores: Leonardo A. Pérez, Aysha Rashid, J. Dale Combs, Pascal Schneider, Andrés Rodríguez, Khalid Salaita and Lisette Leyton

Vacunas bucales y sublinguales: revisión de los sistemas de inmunización y administración de la mucosa oral

Autores: Valeria Trincado, Rikhav P. Gala y Javier O. Morales

El remodelado cardíaco izquierdo evaluado mediante ecocardiografía se asocia con la activación de la rho-quinasa en corredores de larga distancia

Autores: Felipe Contreras-Briceño, Julián Vega, Jorge Mandiola, María Paz Ocaranza, Sebastián Herrera, Manuel Salinas, Rodrigo Fernández, Jorge E. Jalil, Sergio Lavandero, Mario Chiong, Paz Godoy, Pablo F. Castro, Marta Sitges y Luigi Gabrielli

Thy-1 (CD90)-Induced Metastatic Cancer Cell Migration and Invasion Are β3 Integrin-Dependent and Involve a Ca2+/P2X7 Receptor Signaling Axis

Marianne Brenet, Samuel Martínez, Ramón Pérez-Nuñez, Leonardo A. Pérez, Pamela Contreras, Jorge Díaz, Ana María Avalos, Pascal Schneider, Andrew F. G. Quest y Lisette Leyton

Polycystin-1 regulates cardiomyocyte mitophagy

Andrea Ramírez-Sagredo, Clara Quiroga, Valeria Garrido-Moreno, Camila López-Crisosto, Sebastian Leiva-Navarrete, Ignacio Norambuena-Soto, Jafet Ortiz-Quintero, Magda C. Díaz-Vesga, William Perez, Troy Hendrickson, Valentina Parra, Zully Pedrozo, Francisco Altamirano, Mario Chiong, Sergio Lavandero

Light-induced release of the cardioprotective peptide angiotensin-(1–9) from thermosensitive liposomes with gold nanoclusters

Julian Bejarano, Aldo Rojas, Andrea Ramírez-Sagredo, Ana L.Riveros, Francisco Morales-Zavala, Yvo Flores, Jaime A.Riquelme, Fanny Guzman, Eyleen Araya, Mario Chiong, María Paz Ocaranza, Javier O.Morales, María Gabriela Villamizar Sarmiento, Gina Sanchez, Sergio Lavandero y Marcelo J.Kogan

Endoplasmic reticulum−mitochondria coupling increases during doxycycline-induced mitochondrial stress in HeLa cells

Camila Lopez-Crisosto, Alexis Díaz-Vegas, Pablo F. Castro, Beverly A. Rothermel, Roberto Bravo-Sagua & Sergio Lavandero

VCAM-1 as a predictor biomarker in cardiovascular disease

Mayarling Francisca Troncosoa, Jafet Ortiz-Quintero, Valeria Garrido-Morenoa Fernanda Sanhueza-Olivares, Alejandra Guerrero-Moncayo, Mario Chiong, Pablo F.Castro Lorena García, Luigi Gabrielli, Ramón Corbalán, LuisGarrido-Olivares y Sergio Lavandero

NGF-Enhanced Vasculogenic Properties of Epithelial Ovarian Cancer Cells Is Reduced by Inhibition of the COX-2/PGE2 Signaling Axis

Maritza P. Garrido, Iván Hurtado, Manuel Valenzuela-Valderrama, Renato Salvatierra, Andrea Hernández, Margarita Vega, Alberto Selman, Andrew F. G. Quest y Carmen Romero

NAD+ Repletion Reverses Heart Failure with Preserved Ejection Fraction

Dan Tong, Gabriele G Schiattarella, Nan Jiang, Francisco Altamirano, Pamela A Szweda, Abdallah Elnwasany, Dong I Lee, Heesoo Yoo, David A Kass, Luke I Szweda, Sergio Lavandero, Eric Verdin, Thomas G Gillette and Joseph A Hill

Science and Health Policies to Tackle Chronic Diseases in Chile

Bambs C.; Bravo-Sagua R.; Margozzini P.; Lavandero S.

Nuclear accumulation of ?-catenin is associated with endosomal sequestration of the destruction complex and increased activation of Rab5 in oral dysplasia

Reyes Rojas, Montserrat; Peña Oyarzún, Daniel; Silva, Patricio; Venegas, Sebastián; Criollo Céspedes, Alfredo; Torres Gómez, Vicente

Human adipose-derived mesenchymal stem cell-conditioned medium ameliorates polyneuropathy and foot ulceration in diabetic BKS db/db mice

De Gregorio, Cristian; Contador, David; Diaz, Diego; Carcamo, Constanza; Santapau, Daniela; Lobos-Gonzalez, Lorena; Acosta, Cristian; Campero, Mario; Carpio, Daniel; Gabriele, Caterina; Gaspari, Marco; Aliaga-Tobar, Victor; Maracaja-Coutinho, Vinicius; Ezquer, Marcelo; Ezquer, Fernando Ezquer

Effects of preparation on catalytic, magnetic and hybrid micromotors on their functional features and application in gastric cancer biomarker detection

Daniela F.Báez, Gabriel Ramos, Alejandro Corvalán, María Luisa Cordero, Soledad Bollo y Marcelo J.Kogan

Label-Free Oligonucleotide-Based SPR Biosensor for the Detection of the Gene Mutation Causing Prothrombin-Related Thrombophilia

Sierpe, Rodrigo; Kogan, Marcelo J.; Bollo, Soledad Bollo

In vitro evaluation and molecular docking of QS-21 and quillaic acid from Quillaja saponaria Molina as gastric cancer agents

Guzman, Leda; Villalon, Katherine; Jose Marchant, Maria; Elena Tarnok, Maria; Cardenas, Pilar; Aquea, Gisela; Acevedo, Waldo; Padilla, Leandro; Bernal, Giuliano; Molinari, Aurora; Corvalan, Alejandro Corvalán

Exosomes released upon mitochondrial ASncmtRNA knockdown reduce tumorigenic properties of malignant breast cancer cells

Lobos-González L.; Bustos R.; Campos A.; Silva V.; Silva V.; Jeldes E.; Salomon C.; Varas-Godoy M.; Cáceres-Verschae A.; Duran E.; Vera T.; Ezquer F.; Ezquer M.; Burzio, V.A.; Villegas J.

Autophagy Activation in Zebrafish Heart Regeneration

Chávez, Myra N.; Morales, Rodrigo A.; López-Crisosto, Camila; Roa, Juan Carlos; Allende, Miguel L.; Lavandero, Sergio Lavandero

Tabaquismo en el adulto mayor: un freno al envejecimiento saludable en la población chilena

Vidal, Cristina; Padilla, Oslando; Bambs, Claudia

Interface analysis of Ag/n‐type Si contacts in n‐type PERT solar cells

Ferrada, Pablo; Rudolph, Dominik; Portillo, Carlos; Adrian, Adrian; Correa?Puerta, Jonathan; Sierpe, Rodrigo; Campo, Valeria; Flores, Marcos; Corrales, Tomas P.; Henríquez, Ricardo; Kogan, Marcelo J.; Lossen, Jan Lossen

In Vitro Hyperthermia Evaluation of Electrospun Polymer Composite Fibers Loaded with Reduced Graphene Oxide

Ignacio A. Zárate, Héctor Aguilar-Bolados, Mehrdad Yazdani-Pedram, Guadalupe del C. Pizarro y Andrónico Neira-Carrillo

Regional variations in Helicobacter pylori infection, gastric atrophy and gastric cancer risk: The ENIGMA study in Chile

Rolando Herrero, Katy Heise, Johanna Acevedo, Paz Cook, Claudia Gonzalez, Jocelyne Gahona, Raimundo Cortés, Luis Collado, María Enriqueta Beltrán, Marcos Cikutovic, Paula Gonzalez †, Raul Murillo, Marcis Leja, Francis Megraud, Maria de la Luz Hernandez, Sylvaine Barbier, Jin Young Park, Catterina Ferreccio, for the ENIGMA Chile study group

Inhibition of chymotrypsin-like activity of the proteasome by ixazomib prevents mitochondrial dysfunction during myocardial ischemia

Gina Sánchez, Stefanie Chalmers, Xavier Ahumada, Luis Montecinos, Ivonne Olmedo, Veronica Eisner, Ana Riveros, Marcelo J. Kogan, Sergio Lavandero, Zully Pedrozo y Paulina Donoso

Polypharmacy in a semirural community in Chile: Results from Maule Cohort

Ximena Oyarzún-González, Catterina Ferreccio, Erin L Abner, Claudio Vargas, Andrea Huidobro y Pablo Toro

Exploiting the Natural Properties of Extracellular Vesicles in Targeted Delivery towards Specific Cells and Tissues

Pablo Lara, Alan B. Chan, Luis J. Cruz, Andrew F. G. Quest y Marcelo J. Kogan

Drug-Loaded Lipid-Core Micelles in Mucoadhesive Films as a Novel Dosage Form for Buccal Administration of Poorly Water-Soluble and Biological Drugs

Wai-Houng Chou, Ariel Galaz, Miguel O. Jara, Alexander Gamboa y Javier O. Morales

Metformin Reduces NGF-Induced Tumour Promoter Effects in Epithelial Ovarian Cancer Cells

Maritza P. Garrido, Renato Salvatierra, Manuel Valenzuela-Valderrama, Christopher Vallejos, Nicole Bruneau, Andrea Hernández, Margarita Vega, Alberto Selman, Andrew F. G. Quest y Carmen Romero

Role of Epstein-Barr Virus and Human Papillomavirus Coinfection in Cervical Cancer: Epidemiology, Mechanisms and Perspectives

Rancés Blanco, Diego Carrillo-Beltrán, Julio C. Osorio, Gloria M Calaf y Francisco Aguayo

Markers of epithelial-mesenchymal transition in an experimental breast cancer model induced by organophosphorous pesticides and estrogen (Review)

Gloria M. Calaf, Tammy C. Bleak, Juan P. Muñoz y Francisco Aguayo

The non-receptor tyrosine phosphatase type 14 blocks caveolin-1-enhanced cancer cell metastasis

Natalia I. Díaz-Valdivia, Jorge Díaz, Pamela Contreras, América Campos, Victoria Rojas-Celis, Renato A. Burgos-Ravanal, Lorena Lobos-González, Vicente A. Torres, Viviana I. Perez, Balz Frei, Lisette Leyton & Andrew F. G. Quest

β-Hydroxybutyrate Increases Exercise Capacity Associated with Changes in Mitochondrial Function in Skeletal Muscle

Matías Monsalves-Alvarez, Pablo Esteban Morales, Mauricio Castro-Sepulveda, Carlos Sepulveda, Juan Manuel Rodríguez, Mario Chiong, Verónica Eisner, Sergio Lavandero y Rodrigo Troncoso

Neurological soft signs (NSS) and cognitive deficits in HIV associated neurocognitive disorder

Gonzalo Forno,  Fernando Henríquez, María Elena Ceballos, Matías Gonzalez,  Johannes Schröder y PabloToro

Counter-regulatory renin–angiotensin system in cardiovascular disease

Maria Paz Ocaranza, Jaime A. Riquelme, Lorena García, Jorge E. Jalil, Mario Chiong, Robson A. S. Santos y Sergio Lavandero

Design, development and evaluation of nanoemulsion containing avocado peel extract with anticancer potential: A novel biological active ingredient to enrich food

Paulina Cerda Opazo, Martin Gotteland, Felipe A.Oyarzun-Ampuero y Lorena Garcia

A Materials Screening Test of Corrosion Monitoring in LiNO3 Containing Molten Salts as a Thermal Energy Storage Material for CSP Plants

Abdiel Mallco, Carlos Portillo, Marcelo J Kogan, Felipe Galleguillos y Angel G. Fernández

Manipulation of ACE2 expression in COVID-19

Farhan Chaudhry, Sergio Lavandero, Xiang Xie, Basera Sabharwal, Ying-Ying Zheng, Ashish Correa, Jagat Narula y Phillip Levy

EBV miR-BARTs and human lncRNAs: Shifting the balance in competing endogenous RNA networks in EBV-associated gastric cancer

Keila Torres, Natalia Landeros, Ignacio A.Wichmann, Iva Polakovicova, Francisco Aguayo y Alejandro H.Corvalan

The Chile Biliary Longitudinal Study: A Gallstone Cohort

Jill Koshiol, Vanessa Van De Wyngard, Emma E McGee, Paz Cook, Ruth M Pfeiffer, Noldy Mardones, Karie Medina, Vanessa Olivo, Karen Pettit, Sarah S Jackson, Fabio Paredes, Raúl Sanchez, Andrea Huidobro, Miguel Villaseca, Enrique Bellolio, Hector Losada, Juan Carlos Roa, Allan Hildesheim, Juan Carlos Araya, Catterina Ferreccio, for the Chile BiLS Study Group

FoxO1-Dio2 signaling axis governs cardiomyocyte thyroid hormone metabolism and hypertrophic growth

Ferdous, Anwarul; Wang, Zhao, V; Luo, Yuxuan; Li, Dan L.; Luo, Xiang; Schiattarella, Gabriele G.; Altamirano, Francisco; May, Herman, I; Battiprolu, Pavan K.; Nguyen, Annie; Rothermel, Beverly A.; Lavandero, Sergio; Gillette, Thomas G.; Hill, Joseph A.

Gold Nanoparticles Mediate Improved Detection of beta-amyloid Aggregates by Fluorescence

Jara-Guajardo, Pedro; Cabrera, Pablo; Celis, Freddy; Soler, Monica; Berlanga, Isadora; Parra-Munoz, Nicole; Acosta, Gerardo; Albericio, Fernando; Guzman, Fanny; Campos, Marcelo; Alvarez, Alejandra; Morales-Zavala, Francisco; Kogan, Marcelo J.

Occurrence of relevant mycotoxins in food commodities consumed in Chile

Foerster, Claudia; Munoz, Katherine; Delgado-Rivera, Lorena; Rios, Gisela

Evaluation of the chemopreventive potentials of ezetimibe and aspirin in a novel mouse model of gallbladder preneoplasia

Rosa, Lorena; Lobos-Gonzalez, Lorena; Munoz-Durango, Natalia; Garcia, Patricia; Bizama, Carolina; Gomez, Natalia; Gonzalez, Ximena; Wichmann, Ignacio A.; Saavedra, Nicolas; Guevara, Francisca; Villegas, Jaime; Arrese, Marco; Ferreccio, Catterina; Kalergis, Alexis M.; Miquel, Juan Francisco; Espinoza, Jaime A.; Roa, Juan C.

Emerging role of mitophagy in cardiovascular physiology and pathology

Morales P.E.; Arias-Durán C.; Ávalos-Guajardo Y.; Aedo G.; Verdejo H.E.; Parra V.; Lavandero S.

Chitosan-Based Nanoparticles for Intracellular Delivery of ISAV Fusion Protein cDNA into Melanoma Cells: A Path to Develop Oncolytic Anticancer Therapies

Robles-Planells, Claudia; Guerrero, Giselle Sanchez; Barrera-Avalos, Carlos; Matiacevich, Silvia; Rojo, Leonel E.; Pavez, Jorge; Salas-Huenuleo, Edison; Kogan, Marcelo J.; Escobar, Alejandro; Milla, Luis A.; Fernandez, Ricardo; Imarai, Monica; Spencer, Eugenio; Huidobro-Toro, Juan Pablo; Acuna-Castillo, Claudio

Gold nanoparticle based double-labeling of melanoma extracellular vesicles to determine the specificity of uptake by cells and preferential accumulation in small metastatic lung tumors

Lara, Pablo; Palma-Florez, Sujey; Salas-Huenuleo, Edison; Polakovicova, Iva; Guerrero, Simon; Lobos-Gonzalez, Lorena; Campos, America; Munoz, Luis; Jorquera-Cordero, Carla; Varas-Godoy, Manuel; Cancino, Jorge; Arias, Eloisa; Villegas, Jaime; Cruz, Luis J.; Albericio, Fernando; Araya, Eyleen; Corvalan, Alejandro H.; Quest, Andrew F. G.; Kogan, Marcelo J.

Miro1 as a novel regulator of hypertrophy in neonatal rat cardiomyocytes

Conejeros C.; Parra V.; Sanchez G.; Pedrozo Z.; Olmedo I.

Adsorption of bovine serum albumin on gold nanoprisms: interaction and effect of NIR irradiation on protein corona

Bolanos, Karen; Celis, Freddy; Garrido, Carlos; Campos, Marcelo; Guzman, Fanny; Kogan, Marcelo J.; Araya, Eyleen

Circulating Arsenic is Associated with Long-Term Risk of Graft Failure in Kidney Transplant Recipients: A Prospective Cohort Study

Sotomayor, CG; Groothof, D; Vodegel, JJ; Gacitua, TA; Gomes-Neto, AW; Oste, MCJ; Pol, RA; Ferreccio, C; Berger, SP; Chong, G; Slart, RHJA; Rodrigo, R; Navis, GJ; Touw, DJ; Bakker, SJL

Rho-kinase pathway activation and apoptosis in circulating leucocytes in patients with heart failure with reduced ejection fraction

Ocaranza M.P.; Moya J.; Jalil J.E.; Lavandero S.; Kalergis A.M.; Molina C.; Gabrielli L.; Godoy I.; Córdova S.; Castro P.; Mac Nab P.; Rossel V.; García L.; González J.; Mancilla C.; Fierro C.; Farías L.

Increased production of functional small extracellular vesicles in senescent endothelial cells

Riquelme J.A.; Takov K.; Santiago-Fernández C.; Rossello X.; Lavandero S.; Yellon D.M.; Davidson S.M.

Antimicrobial Resistance Gene Prevalence in a Population of Patients with Advanced Dementia Is Related to Specific Pathobionts

Rowan-Nash A.D.; Araos R.; D'Agata E.M.C.; Belenky P.

Sarcoplasmic reticulum and calcium signaling in muscle cells: Homeostasis and disease

Bravo-Sagua R.; Parra V.; Muñoz-Cordova F.; Sanchez-Aguilera P.; Garrido V.; Contreras-Ferrat A.; Chiong M.; Lavandero S.

New emerging roles of Polycystin-2 in the regulation of autophagy

Peña-Oyarzun D.; Batista-Gonzalez A.; Kretschmar C.; Burgos P.; Lavandero S.; Morselli E.; Criollo A.

Intranasal administration of gold nanoparticles designed to target the central nervous system: Fabrication and comparison between nanospheres and nanoprisms

Gallardo-Toledo, Eduardo; Tapia-Arellano, Andreas; Celis, Freddy; Sinai, Tomer; Campos, Marcelo; Kogan, Marcelo J.; Sintov, Amnon C.

Curcumin rescues breast cells from epithelial?mesenchymal transition and invasion induced by anti?miR?34ª

Gallardo M.; Kemmerling U.; Aguayo F.; Bleak T.C.; Muñoz J.P.; Calaf, G. M.

Improving cell penetration of gold nanorods by using an amphipathic arginine rich peptide

Riveros A.L.; Eggeling C.; Riquelme S.; Adura C.; López-Iglesias C.; Guzmán F.; Araya E.; Almada M.; Juárez J.; Valdez M.A.; Fuentevilla, I.A.; López O.; Kogan M.J.

Wnt/beta-Catenin Signaling in Oral Carcinogenesis

Reyes, Montserrat; Flores, Tania; Betancur, Diego; Pena-Oyarzun, Daniel; Torres, Vicente A.

Moderate Aerobic Exercise Training Prevents the Augmented Hepatic Glucocorticoid Response Induced by High-Fat Diet in Mice

Dassonvalle, Jonatan; Diaz-Castro, Francisco; Donoso-Barraza, Camila; Sepulveda, Carlos; Pino-de la Fuente, Francisco; Pino, Pamela; Espinosa, Alejandra; Chiong, Mario; Llanos, Miguel; Troncoso, Rodrigo

Loss of Caveolin-1 Is Associated with a Decrease in Beta Cell Death in Mice on a High Fat Diet

Lillo Urzua, Paloma; Nunez Murillo, Olinda; Castro-Sepulveda, Mauricio; Torres-Quintana, Maria A.; Lladser Caldera, Alvaro; Quest, Andrew F. G.; Espinoza Robles, Carolina; Llanos Vidal, Paola; Wehinger, Sergio

Calcium-Sensing Receptor in Adipose Tissue: Possible Association with Obesity-Related Elevated Autophagy

Mattar, Pamela; Sanhueza, Sofia; Yuri, Gabriela; Briones, Lautaro; Perez-Leighton, Claudio; Rudich, Assaf; Lavandero, Sergio; Cifuentes, Mariana