Publicaciones

Cohort Profile: The Maule Cohort (MAUCO)

Ferreccio, Catterina; Huidobro, Andrea; Cortés, Sandra; Bambs, Claudia; Toro, Pablo; Van De Wyngard, Vanessa; Acevedo, Johanna; Paredes, Fabio; Venegas, Pía; Verdejo, Hugo; Oyarzún-González, Ximena; Cook, Paz; Castro, Pablo F; Foerster, Claudia; Vargas, Claudio; Koshiol, Jill; Araya, Juan Carlos; Cruz, Francisco; Corvalán, Alejandro H; Quest, Andrew F; et al.

Gallbladder and extrahepatic bile duct cancers in the Americas: Incidence and mortality patterns and trends

Miranda-Filho A.; Piñeros M.; Ferreccio C.; Adsay V.; Soerjomataram I.; Bray F.; Koshiol J.

Merkel cell polyomavirus detected in head and neck carcinomas from Chile

Muñoz J.P.; Blanco R.; Osorio J.C.; Oliva C.; Diaz M.J.; Carrillo-Beltrán D.; Aguayo R.; Castillo A.; Tapia, J.C.; Calaf, G. M.; Gaggero A.; Aguayo F.

Chaperone Mediated Autophagy Degrades TDP-43 Protein and Is Affected by TDP-43 Aggregation

Ormeño F.; Hormazabal J.; Moreno J.; Riquelme F.; Rios J.; Criollo A.; Albornoz A.; Alfaro I.E.; Budini M.

Application of Force to a Syndecan-4 Containing Complex With Thy-1-alpha(V)beta(3)Integrin Accelerates Neurite Retraction

Burgos-Bravo, Francesca; Martinez-Meza, Samuel; Quest, Andrew F. G.; Wilson, Christian A. M.; Leyton, Lisette

Analytical and Clinical Validation for RT-qPCR Detection of SARS-CoV-2 Without RNA Extraction

Miranda, Jose P.; Osorio, Javiera; Videla, Mauricio; Angel, Gladys; Camponovo, Rossana; Henriquez-Henriquez, Marcela

New Insights on the Role of Lipid Metabolism in the Metabolic Reprogramming of Macrophages

Batista-Gonzalez A.; Vidal R.; Criollo A.; Carreño L.J.

Editorial: User-Friendly Tools Applied to Genetics or Systems Biology

Nakaya, Helder I.; Thakar, Juilee; Maracaja-Coutinho, Vinicius

Moderate Exercise in Spontaneously Hypertensive Rats Is Unable to Activate the Expression of Genes Linked to Mitochondrial Dynamics and Biogenesis in Cardiomyocytes

Quiroga, Clara; Mancilla, Georthan; Oyarzun, Ingrid; Tapia, Anita; Caballero, Mia; Gabrielli, Luigi A.; Valladares-Ide, Denisse; del Campo, Andrea; Castro, Pablo F.; Verdejo, Hugo E

Low nanomolar concentrations of a quercetin oxidation product, which naturally occurs in onion peel, protect cells against oxidative damage

Fuentes J.; Arias-Santé M.F.; Atala E.; Pastene E.; Kogan M.J.; Speisky H.

Delivery of ionizable hydrophilic drugs based on pharmaceutical formulation of ion pairs and ionic liquids

Gamboa, Alexander; Schuessler, Nina; Soto-Bustamante, Eduardo; Romero-Hasler, Patricio; Meinel, Lorenz; Morales, Javier O.

Is Mitochondrial Dysfunction a Common Root of Noncommunicable Chronic Diseases?

Diaz-Vegas, Alexis; Sanchez-Aguilera, Pablo; Krycer, James R.; Morales, Pablo E.; Monsalves-Alvarez, Matias; Cifuentes, Mariana; Rothermel, Beverly A.; Lavandero, Sergio

Mitochondrial transfer from MSCs to T cells induces Treg differentiation and restricts inflammatory response

Court, Angela C.; Le-Gatt, Alice; Luz-Crawford, Patricia; Parra, Eliseo; Aliaga-Tobar, Victor; Federico Batiz, Luis; Contreras, Rafael A.; Ignacia Ortuzar, Maria; Kurte, Monica; Elizondo-Vega, Roberto; Maracaja-Coutinho, Vinicius; Pino-Lagos, Karina; Figueroa, Fernando E.; Khoury, Maroun

Early left atrial dysfunction is associated with suboptimal cardiovascular health

Ocaranza M.P.; Bambs C.; Salinas M.; Matamala, C; Garcia L.; Troncoso R.; Pedrozo Z.; Huidobro A.; Venegas P.; Paredes F.; Giacaman A.; Zalaquett R.; Chiong M.; Verdejo H.E.; Ferreccio C.; Lavandero S.; Castro P.F.; Gabrielli L.

Inhibition of beta-amyloid Aggregation of Ugni molinae Extracts

Jara-Moreno, Daniela; Riveros, Ana L.; Barriga, Andres; Kogan, Marcelo J.; Delporte, Carla.

Effect of Functionalized Multiwalled CNTs on the Selective Formation of Calcium Oxalate Crystals by Electrocrystallization

Vargas-Fernández A.; Sánchez M.; Dáz-Soler F.; Vásquez-Quitral P.; Yazdani-Pedram M.; Neira-Carrillo A.

Validity and Performance of the Patient Health Questionnaire (PHQ-2) for Screening of Depression in a Rural Chilean Cohort

Caneo C.; Toro P.; Ferreccio C.; Bambs C.; Cortés S.; Paredes F.; Huidobro A.; Venegas P.; Acevedo J.; the Mauco Research Team

Preoperative solubleVCAM-1 contributes to predict late mortality after coronary artery surgery

Corbalan, Ramon; Garcia, Mauricio; Garrido-Olivares, Luis; Garcia, Lorena; Perez, Gonzalo; Mellado, Rosemarie; Zalaquett, Ricardo; Chiong, Mario; Quitral, Jorge; Lavandero, Sergio

Angiotensin-(1–9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway

Sotomayor-Flores C.; Rivera-Mejías P.; Vásquez-Trincado C.; López-Crisosto C.; Morales P.E.; Pennanen C.; Polakovicova I.; Aliaga-Tobar V.; García L.; Roa, J.C; Rothermel B.A.; Maracaja-Coutinho V.; Ho-Xuan H.; Meister G.; Chiong M.; Ocaranza M.P.; Corvalán A.H.; Parra V.; Lavandero S.

Caveolin-1 suppresses tumor formation through the inhibition of the unfolded protein response

Diaz, Maria I.; Diaz, Paula; Bennett, Jimena Castillo; Urra, Hery; Ortiz, Rina; Orellana, Pamela Contreras; Hetz, Claudio; Quest, Andrew F. G.

Rho kinase cascade activation in circulating leukocytes in patients with diabetes mellitus type 2

Paz Ocaranza, Maria; Valderas, Patricio; Moya, Jackeline; Gabrielli, Luigi; Godoy, Ivan; Cordova, Samuel; Mac Nab, Paul; Garcia, Lorena; Farias, Luis; Jalil, Jorge E.

NGF-Enhanced Vasculogenic Properties of Epithelial Ovarian Cancer Cells Is Reduced by Inhibition of the COX-2/PGE(2) Signaling Axis

Garrido M.P.; Hurtado I.; Valenzuela-Valderrama M.; Salvatierra R.; Hernández A.; Vega M.; Selman A.; Quest A.F.G.; Romero C.

Human Papillomavirus 16 E7 Promotes EGFR/PI3K/AKT1/NRF2 Signaling Pathway Contributing to PIR/NF-kappa B Activation in Oral Cancer Cells

Carrillo-Beltran, Diego; Munoz, Juan P.; Guerrero-Vasquez, Nahir; Blanco, Rances; Leon, Oscar; de Souza Lino, Vanesca; Tapia, Julio C.; Maldonado, Edio; Dubois-Camacho, Karen; Hermoso, Marcela A.; Corvalan, Alejandro H.; Calaf, Gloria M.; Boccardo, Enrique; Aguayo, Francisco

High-Risk Human Papillomavirus and Tobacco Smoke Interactions in Epithelial Carcinogenesis

Aguayo, Francisco; Munoz, Juan P.; Perez-Dominguez, Francisco; Carrillo-Beltran, Diego; Oliva, Carolina; Calaf, Gloria M.; Blanco, Rances; Nunez-Acurio, Daniela

Competing Endogenous RNA Networks in the Epithelial to Mesenchymal Transition in Diffuse-Type of Gastric Cancer

Landeros, Natalia; Santoro, Pablo M.; Carrasco-Avino, Gonzalo; Corvalan, Alejandro H.

Caveolin-1-Mediated Tumor Suppression Is Linked to Reduced HIF1 alpha S-Nitrosylation and Transcriptional Activity in Hypoxia

Sanhueza, Carlos; Bennett, Jimena Castillo; Valenzuela-Valderrama, Manuel; Contreras, Pamela; Lobos-Gonzalez, Lorena; Campos, America; Wehinger, Sergio; Lladser, Alvaro; Kiessling, Rolf; Leyton, Lisette; Quest, Andrew F. G.

A Molecular Stratification of Chilean Gastric Cancer Patients with Potential Clinical Applicability

Pinto, Mauricio P.; Cordova-Delgado, Miguel; Retamal, Ignacio N.; Munoz-Medel, Matias; Loreto Bravo, M.; Duran, Doris; Villanueva, Francisco; Sanchez, Cesar; Acevedo, Francisco; Mondaca, Sebastian; Koch, Erica; Ibanez, Carolina; Galindo, Hector; Madrid, Jorge; Nervi, Bruno; Pena, Jose; Torres, Javiera; Owen, Gareth, I; Corvalan, Alejandro H.; Armisen, Ricardo; et al.

A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus-positive and -Negative Cervical Precancers

CF, RL5, virus, papiloma humano

Caveolin-1 function at the plasma membrane and in intracellular compartments in cancer

Simon, L.; Campos, A.; Leyton, L.; Quest, A. F. G.

Multicentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America: the ESTAMPA screening study protocol

Almonte, Maribel; Murillo, Raúl; Sánchez, Gloria Inés; González, Paula; Ferrera, Annabelle; Picconi, María Alejandra; Wiesner, Carolina; Cruz-Valdez, Aurelio; Lazcano-Ponce, Eduardo; Jerónimo, Jose; Ferreccio, Catterina; Kasamatsu, Elena; Mendoza, Laura; Rodríguez, Guillermo; Calderón, Alejandro; Venegas, Gino; Villagra, Verónica; Tatti, Silvio; Fleider, Laura; Terán, Carolina; et al.

Role of FoxO3a as a negative regulator of the cardiac myofibroblast conversion induced by TGF-?1

Vivar R.; Humeres, C.; Anfossi R.; Bolivar S.; Catalán M.; Hill J.; Lavandero S.; Diaz-Araya G.

Inhibition of the proteasome preserves Mitofusin-2 and mitochondrial integrity, protecting cardiomyocytes during ischemia-reperfusion injury

Olmedo I.; Pino G.; Riquelme J.A.; Aranguiz P.; Díaz M.C.; López-Crisosto C.; Lavandero S.; Donoso P.; Pedrozo Z.; Sánchez G.

Exercise regulates lipid droplet dynamics in normal and fatty liver

Pino-de la Fuente, Francisco; Quezada, Laura; Sepulveda, Carlos; Monsalves-Alvarez, Matias; Rodriguez, Juan M.; Sacristan, Camila; Chiong, Mario; Llanos, Miguel; Espinosa, Alejandra; Troncoso, Rodrigo

Angiotensin-(1-9) prevents vascular remodeling by decreasing vascular smooth muscle cell dedifferentiation through a FoxO1-dependent mechanism

Norambuena-Soto, Ignacio; Ocaranza, Maria Paz; Cancino-Arenas, Nicole; Sanhueza-Olivares, Fernanda; Villar-Fincheira, Paulina; Leiva-Navarrete, Sebastian; Mancilla-Medina, Cristian; Moya, Jacqueline; Novoa, Ulises; Jalil, Jorge E.; Castro, Pablo F.; Lavandero, Sergio; Chiong, Mario

The 5’ untranslated region of the anti-apoptotic protein Survivin contains an inhibitory upstream AUG codon

Palavecino C.E.; Carrasco-Véliz N.; Quest A.F.G.; Garrido M.P.; Valenzuela-Valderrama M.

Pro-fibrotic effect of oxidized LDL in cardiac myofibroblasts

Villa M.; Cerda-Opazo P.; Jimenez-Gallegos D.; Garrido-Moreno V.; Chiong M.; Quest A.F.; Toledo J.; Garcia L.

The Association of Ascorbic Acid, Deferoxamine and N-Acetylcysteine Improves Cardiac Fibroblast Viability and Cellular Function Associated with Tissue Repair Damaged by Simulated Ischemia/Reperfusion

Parra-Flores P.; Riquelme J.A.; Valenzuela-Bustamante P.; Leiva-Navarrete S.; Vivar R.; Cayupi-Vivanco J.; Castro E.; Espinoza-Pérez C.; Ruz-Cortés F.; Pedrozo Z.; Lavandero S.; Rodrigo R.; Diaz-Araya G.

Down syndrome and alzheimer’s disease: Common molecular traits beyond the amyloid precursor protein

Gomez W.; Morales R.; Maracaja-Coutinho V.; Parra V.; Nassif M.

Phantom Systole: A Failed Ejection Phenomenon between Pulsus Alternans and Systolic Aortic Regurgitation

Germán Ramos G, MD Juan Bulnes M, MD Alejandro Paredes C, MD Luigi Gabrielli N, MD

Calcium-Sensing Receptor in Adipose Tissue: Possible Association with Obesity-Related Elevated Autophagy

Pamela Mattar, Sofía Sanhueza, Gabriela Yuri, Lautaro Briones, Claudio Perez-Leighton, Assaf Rudich, Sergio Lavandero y Mariana Cifuentes

Liberación inducida por la luz del péptido cardioprotector angiotensina- (1-9) de liposomas termosensibles con nanoclusters de oro

JulianBejarano, AldoRojas, AndreaRamírez-Sagredo, Ana L.Riveros, FranciscoMorales-Zavala, YvoFlores,, Jaime Riquelme,, FannyGuzman,,, EyleenAraya, MarioChiong, María PazOcaranza, Javier O.Morales, María Gabriela Villamizar Sarmiento, Gina Sanchez, SergioLavandero y Marcelo J.Kogan

Preoperative soluble VCAM-1 contributes to predict late mortality after coronary artery surgery

Ramon Corbalán, Mauricio García, Luis Garrido-Olivares, Lorena García, Gonzalo Pérez, Rosemarie Mellado, Ricardo Zalaquett, Mario Chiong, Jorge Quitral, Sergio Lavandero.

Nuclear accumulation of β‐catenin is associated with endosomal sequestration of the destruction complex and increased activation of Rab5 in oral dysplasia

Autores: Montserrat Reyes, Daniel Peña‐Oyarzún, Patricio Silva, Sebastián Venegas, Alfredo Criollo y Vicente A. Torres

β-Hydroxybutyrate Increases Exercise Capacity Associated with Changes in Mitochondrial Function in Skeletal Muscle

Autores: Matías Monsalves-Alvarez,Pablo Esteban Morales, Mauricio Castro-Sepulveda,Carlos Sepulveda, Juan Manuel Rodriguez, Mario Chiong, Verónica Eisner, Sergio Lavandero and Rodrigo Troncoso.

Polypharmacy in a semirural community in Chile: Results from Maule Cohort

Ximena Oyarzún-González, Catterina Ferreccio, Erin L Abner, Claudio Vargas, Andrea Huidobro, Pablo Toro

Angiotensin-(1–9) prevents vascular remodeling by decreasing vascular smooth muscle cell dedifferentiation through a FoxO1-dependent mechanism

Ignacio Norambuena Soto, Maria Paz Ocaranza, Nicole Cancino-Arenas, Fernanda Sanhueza Olivares, Paulina Villar Fincheira, Sebastian Leiva Navarrete, Cristian Mancilla Medina, Jacqueline Moya, Ulises Novoa, Jorge E.Jalil, Pablo F.Castro, Sergio Lavandero y MarioChiong

Syndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells Syndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells

Alejandra Valdivia, Areli Cárdenas, Marianne Brenet, Horacio Maldonado, Milene Kong, Jorge Díaz, Keith Burridge, Pascal Schneider, Alejandra San Martín, Rafael García-Mata, Andrew F. G. Quest & Lisette Leyton

Src-family kinase inhibitors block early steps of caveolin-1-enhanced lung metastasis by melanoma cells

Rina Ortiz, Jorge Díaz, Natalia Díaz-Valdivia, Samuel Martínez, Layla Simón, Pamela Contreras, Lorena Lobos-González, Simón Guerrero, Lisette Leyton, Andrew F G Quest

Gold Nanoparticles Mediate Improved Detection of β-amyloid Aggregates by Fluorescence

Pedro Jara-Guajardo, Pablo Cabrera, Freddy Celis, Mónica Soler, Isadora Berlanga, Nicole Parra-Muñoz, Gerardo Acosta, Fernando Albericio, Fanny Guzman, Marcelo Campos, Alejandra Alvarez, Francisco Morales-Zavala, Marcelo J Kogan

Effects of preparation on catalytic, magnetic and hybrid micromotors on their functional features and application in gastric cancer biomarker detection

Daniela F.Báez, Gabriel Ramos, Alejandro Corvalán, María Luisa Cordero, Soledad Bollo y Marcelo J.Kogan

Gold nanoparticle based double-labeling of melanoma extracellular vesicles to determine the specificity of uptake by cells and preferential accumulation in small metastatic lung tumors

Autores: Pablo Lara, Sujey Palma-Florez, Edison Salas-Huenuleo, Iva Polakovicova, Simón Guerrero, Lorena Lobos-González, América Campos, Luis Muñoz, Carla Jorquera-Cordero, Manuel Varas-Godoy, Jorge Cancino, Eloísa Arias, Jaime Villegas, Luis J. Cruz, Fernando Albericio, Eyleen Araya, Alejandro H. Corvalán, Andrew FG Quest y Marcelo J. Kogan

Gallbladder and extrahepatic bile duct cancers in the Americas: Incidence and mortality patterns and trends

Autores: Adalberto Miranda ‐ Filho, Marion Piñeros, Catterina Ferreccio, Volkan Adsay, Isabelle Soerjomataram, Freddie Bray y Jill Koshiol

The non-receptor tyrosine phosphatase type 14 blocks caveolin-1-enhanced cancer cell metástasis

Autores: Natalia I. Díaz-Valdivia, Jorge Díaz, Pamela Contreras, América Campos, Victoria Rojas-Celis, Renato A. Burgos-Ravanal, Lorena Lobos-González, Vicente A. Torres, Viviana I. Perez, Balz Frei, Lisette Leyton y Andrew F. G. Quest

Human Papillomavirus 16 E7 Promotes EGFR/PI3K/AKT1/NRF2 Signaling Pathway Contributing to PIR/NF-κB Activation in Oral Cancer Cells

Autores: Diego Carrillo-Beltrán, Juan P Muñoz , Nahir Guerrero-Vásquez , Rancés Blanco, Oscar León, Vanesca de Souza Lino, Julio C Tapia, Edio Maldonado, Karen Dubois-Camacho, Marcela A Hermoso, Alejandro H Corvalán, Gloria M Calaf, Enrique Boccardo, Francisco Aguayo

webCEMiTool: Co-expression Modular Analysis Made Easy Frontiers in Genetics

Cardozo LE, Russo PST, Gomes-Correia B, Araujo-Pereira M, Sepúlveda Hermosilla G, Maracaja Coutinho V, Nakaya H

TLR4, but Neither Dectin-1 nor Dectin-2, Participates in the Mollusk Hemocyanin-Induced Proinflammatory Effects in Antigen-Presenting Cells From Mammals. Front Immunol

Jiménez JM, Salazar ML, Arancibia S, Villar J, Salazar F, Brown GD, Lavelle EC, Martínez-Pomares L, Ortiz-Quintero J, Lavandero S, Manubens A, Becker MI.

TGF-β1 induced up-regulation of B1 kinin receptor promotes antifibrotic activity in rat cardiac myofibroblasts Mol Biol Rep

Catalán M, Aránguiz P, Boza P, Olmedo I, Humeres C, Vivar R, Anfossi R, Ayala P, Espinoza C, Lavandero S, Díaz-Araya G

Prediction of MicroRNAs in the Epstein–Barr Virus Reveals Potential Targets for the Viral Self-Regulation Indian Journal of Microbiology

Serrano Solis V, Carlos AC, Maracaja Coutinho V, de Farias ST

Curcumin decreases epithelial‑mesenchymal transition by a Pirin‑dependent mechanism in cervical cancer cells Oncology Reports

Victor Aedo Aguilera, Diego Carrillo Beltrán, Gloria M. Calaf, Juan P. Muñoz, Nahir Guerrero, Julio C. Osorio, Julio C. Tapia, Oscar León, Hector R. Contreras. Francisco Aguayo

Polycystin-2 Is Required for Starvation- and Rapamycin-Induced Atrophy in Myotubes Front Endocrinol

Kretschmar C, Peña-Oyarzun D, Hernando C, Hernández-Moya N, Molina-Berríos A, Hernández-Cáceres MP, Lavandero S, Budini M, Morselli E, Parra V, Troncoso R, Criollo A.

Polyphenolic Composition and Hypotensive Effects of Parastrephia quadrangularis (Meyen) Cabrera in Rat. Antioxidants (Basel). 2019 Nov 27; 8(12). pii: E591.

Cifuentes F, Palacios J1, R Nwokocha C, Bórquez J, Simirgiotis MJ, Norambuena I, Chiong M, Paredes A.

Palmitic Acid Reduces the Autophagic Flux and Insulin Sensitivity Through the Activation of the Free Fatty Acid Receptor 1 (FFAR1) in the Hypothalamic Neuronal Cell Line N43/5. Front Endocrinol

Hernández Cáceres MP, Toledo Valenzuela L, Díaz Castro F, Ávalos Y, Burgos P, Narro C, Peña Oyarzun D, Espinoza Caicedo J, Cifuentes Araneda F, Navarro Aguad F, Riquelme C, Troncoso R, Criollo A, Morselli E.

Polycystin-1 Assembles with Kv Channels to Govern Cardiomyocyte Repolarization and Contractility Circulation.

Altamirano F, Schiattarella GG, French KM, Kim SY, Engelberger F, Kyrychenko S, Villalobos E, Tong D, Schneider JW, Ramirez-Sarmiento CA, Lavandero S, Gillette TG, Hill JA

Nitrosative stress drives heart failure with preserved ejection fraction. Nature

Schiattarella GG, Altamirano F, Tong D, French KM, Villalobos E, Kim SY, Luo X, Jiang N, May HI, Wang ZV, Hill TM, Mammen PPA, Huang J, Lee DI, Hahn VS, Sharma K, Kass DA, Lavandero S, Gillette TG, Hill JA.

Long non-coding RNAs are involved in multiple immunological pathways in response to vaccination PNAS

De Lima D, Cardozo LE, Maracaja Coutinho V, Suhrbier A, Mane K, Jeffries D, Silveira ELV, Amaral PP, Rappuoli R, De Silva TI, NakayaHI2

GDF-11 prevents cardiomyocyte hypertrophy by maintaining the sarcoplasmic reticulum-mitochondria communication. Pharmacol Res

Garrido Moreno V, Díaz Vegas A, López Crisosto C, Troncoso MF, Navarro Marquez M, García L, Estrada M, Cifuentes M, Lavandero S.

Chaperone Mediated Autophagy in the Crosstalk of Neurodegenerative Diseases and Metabolic Disorders Front Endocrinol

Alfaro IE, Albornoz A, Molina A, Moreno J, Cordero K, Criollo A, Budini M.

Bafilomycin-A1 and ML9 exert different lysosomal actions to induce cell death. Curr Mol Pharmacol

Shaikh S, Nandy SK, Canti C, Lavandero S

Assessing the Impact of Sample Heterogeneity on Transcriptome Analysis of Human Diseases Using MDP Webtool. Front Genet

Gonçalves ANA, Lever M, Russo PST, Gomes Correia B, Urbanski AH, Pollara G, Noursadeghi M, Maracaja-Coutinho V, Nakaya HI.

Fibroblast Primary Cilia Are Required for Cardiac Fibrosis Circulation.

Villalobos E, Criollo A, Schiattarella GG, Altamirano F, French KM, May HI, Jiang N, Nguyen NUN, Romero D, Roa JC, García L, Diaz-Araya G, Morselli E, Ferdous A, Conway SJ, Sadek HA, Gillette TG, Lavandero S, Hill JA.

Angiotensin II-Regulated Autophagy Is Required for Vascular Smooth Muscle Cell Hypertrophy Front. Pharmacol

David Mondaca Ruff, Jaime A. Riquelme, Clara Quiroga, Ignacio Norambuena Soto, Fernanda Sanhueza Olivares, Paulina Villar Fincheira, Tomás Hernández Díaz, Nicole Cancino Arenas, Alejandra San Martin, Lorena García, Sergio Lavandero, Mario Chiong

Effect of Early Normotension with Olmesartan on Rho-kinase Activity in Hypertensive Patients. Curr Vasc Pharmacol.

Cantin C, Jalil JE, Bulnes JF, Novoa U, MacNab P, Godoy I, Córdova S, Gabrielli L, Ocaranza MP.

Ionic Nanocomplexes of Hyaluronic Acid and Polyarginine to Form Solid Materials: A Green Methodology to Obtain Sponges with Biomedical Potential Nanomaterials (Basel)

Villamizar Sarmiento MG, Moreno Villoslada, Martínez S, Giacaman A, Miranda V, Vidal A, Orellana SL, Concha M, Pavicic F, Lisoni JG, Leyton L, Oyarzun Ampuero FA.

Preface to Advances in Thin Film Technologies in Drug Delivery Int J Pharm.

Gala RP, Morales JO, McConville JT

Magnesium-doped zinc oxide nanoparticles alter biofilm formation of Proteus mirabilis Nanomedicine (Lond)

Victoria Iribarnegaray, Nicolas Navarro, Luciana Robino, Pablo Zunino, Javier Morales & Paola Scavone

Encapsulation of Iron Oxide Nanoparticles and Oil-in-Water Nanocarriers in Microgels with Biomedical Potential J Nanosci Nanotechnol

Álvarez Acevedo G, Inostroza Riquelme M, Chornik B, Flores M, Oyarzun Ampuero F

«Functionalized Multiwalled CNTs in Classical and Nonclassical CaCO3 Crystallization» Nanomaterials

Andrónico Neira Carrillo, Patricio Vásquez Quitral, Marianela Sánchez ,Masoud Farhadi Khouzani, Héctor Aguilar Bolados, Mehrdad Yazdani Pedram Helmut Cölfen

DETERMINATION OF THE POTENCY OF HEXYL–CIPROFLOXACIN MOLECULES THAT INTERACT WITH GOLD NANOPARTICLES IN A REVERSIBLE MANNER IET Nanobiotechnology

Montero F, Kogan M, Montenegro I, Guzman F, Navarrete S, Parra C, Seeger M2.

Development of Novel EE/Alginate Polyelectrolyte Complex Nanoparticles for Lysozyme Delivery: Physicochemical Properties and In Vitro Safety. Pharmaceutics

Sepúlveda Rivas S, Fritz HF, Valenzuela C, Santiago CA, Morales JO

Capping gold nanoparticles with albumin to improve their biomedical properties INTERNATIONAL JOURNAL OF NANOMEDICINE

Bolanos K; Kogan MJ; Araya E

Amino Acid-Functionalized Polyelectrolyte Films as Bioactive Surfaces for Cell Adhesion ACS Appl Mater Interfaces

Leal MS, Briones X, Villalobos V, Queneau Y, Leiva A, Ríos HE, Pavez J, Silva CP, Carrasco C, Neira-Carrillo A, Roth AD, Tamayo L, Urzúa MD

Editorial commentary: Cardiometabolic diseases and gut microbiota-removing the veil Trends Cardiovascular Medicine

Riquelme JA, Ferreccio C, Lavandero S

A New Methodology to Create Polymeric Nanocarriers Containing Hydrophilic Low Molecular-Weight Drugs: A Green Strategy Providing a Very High Drug Loading Mol Pharm

MK Villamizar Sarmiento MG, Molina Soto EF, Guerrero J, Shibue T, Nishide H, Moreno Villoslada I, Oyarzun Ampuero FA

Socioeconomic status and the association between arsenic exposure and type 2 diabetes Environ Res

Eick SM, Ferreccio C, Acevedo J, Castriota F, Cordero JF, Roh T, Smith AH, Smith MT, Steinmaus C

Frailty and health risks in an agricultural population, Chile 2014-2017 Arch Gerontol Geriatr.

Bustamante Ara N, Villarroel L, Paredes F, Huidobro A, Ferreccio C.

Editorial: Neurological Soft Signs in Neuropsychiatric Conditions Front Psychiatry

Toro P, Schröder J

Cardiovascular Disease Prognostic Models in Latin America and the Caribbean: A Systematic Review Glob Heart

Carrillo Larco RM, Altez Fernandez C, Pacheco Barrios N, Bambs C, Irazola V, Miranda JJ, Daniel G, Perel P

Assessment of Gastritis and Gastric Cancer Risk in the Chilean Population Using the OLGA System Pathology & Oncology Research

Bellolio E, Riquelme I, Riffo Campos AL, Rueda C, Ferreccio C, Villaseca M, Brebi P, Muñoz S, Araya JC

An integrated study of health, environmental and socioeconomic indicators in a mining-impacted community exposed to metal enrichment Environ Geochem Health

Moya PM, Arce GJ, Leiva C, Vega AS, Gutiérrez S, Adaros H, Muñoz L, Pastén PA, Cortés S

AT2 Receptor Mediated Activation of the Tyrosine Phosphatase PTP1B Blocks Caveolin-1 Enhanced Migration, Invasion and Metastasis of Cancer Cells. Cancers

AQ-SL-PC Martínez-Meza S, Díaz J, Sandoval-Bórquez A, Valenzuela-Valderrama M, Díaz-Valdivia N, Rojas-Celis V, Contreras P, Huilcaman R, Ocaranza MP, Chiong M, Leyton L, Lavandero S, Quest AFG.

Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER-mitochondria communication during the early phase of ER stress. Cell Death Differ

Bravo Sagua R, Parra V, Ortiz Sandoval C, Navarro Marquez M, Rodríguez AE, Diaz Valdivia N, Sanhueza C, Lopez Crisosto C, Tahbaz N, Rothermel BA, Hill JA, Cifuentes M, Simmen T, Quest AFG, Lavandero S.

«Variability in Genomic and Virulent Properties of Porphyromonas gingivalis Strains Isolated From Healthy and Severe Chronic Periodontitis Individuals» Frontiers in Cellular and Infection Microbiology

Mendez K., Hoare A., Soto C., Buguelo I., Olivera M., Meneses C., Pérez-Donoso JM., Castro-Nallar E., Bravo D

The Netrin-4/Laminin γ1/Neogenin-1 complex mediates migration in SK-N-SH neuroblastoma cells Cell Adh Migr

Villanueva, A., Puvogel, S., Lois, P., Muñoz, E., Ramírez, M., Lubieniecki, F., Casco, F., Gallegos, I., García, J., Sanchez-Gomez, P., Torres V.A., Palma V.

Coagulation Factor Xa Promotes Solid Tumor Growth, Experimental Metastasis and Endothelial Cell Activation. Cancers

Arce M, Pinto MP, Galleguillos M, Muñoz C, Lange S, Ramirez C, Erices R, Gonzalez P, Velasquez E, Tempio F, Lopez MN, Salazar Onfray F, Cautivo K, Kalergis AM, Cruz S, Lladser Á, Lobos González L, Valenzuela G, Olivares N, Sáez C, Koning T, Sánchez FA, Fuenzalida P, Godoy A, Contreras Orellana P, Leyton L, Lugano R, Dimberg A, Quest AFG, Owen GI.

Role of glycosylation in hypoxia-driven cell migration and invasion Cell Adh Migr

Arriagada C, Silva P, Torres V.A.

Nuclear localization of β-catenin and expression of target genes are associated with increased Wnt secretion in oral dysplasia. Oral Oncol

Reyes M, Peña Oyarzún D, Maturana, A. Torres V.A

The Helicobacter pylori Urease Virulence Factor Is Required for the Induction of Hypoxia-Induced Factor-1α in Gastric Cells. Cancers

Valenzuela Valderrama M, Cerda Opazo P, Backert S, González MF, Carrasco Véliz N, Jorquera Cordero C, Wehinger S, Canales J, Bravo D, Quest AFG.

Focal adhesion kinase-dependent activation of the early endocytic protein Rab5 is associated with cell migration. J Biol Chem

Arriagada, C., Silva, P., Millet, M., Solano, L., Moraga, C. & Torres, V.A.

Chronic Inflammation as a Link between Periodontitis and Carcinogenesis Mediators Inflamm.

Hoare A, Soto C, Rojas V, Bravo D

Histatin-1 counteracts the cytotoxic and antimigratory effects of zoledronic acid in endothelial and osteoblast-like cells J Periodontol

Castro, M., Torres, P., Solano, L., Córdova, L. & Torres, V.A.

Cell Intrinsic and Extrinsic Mechanisms of Caveolin-1-Enhanced Metastasis. Biomolecules.

Campos A, Burgos Ravanal R, González MF, Huilcaman R, Lobos González L, Quest AFG.

Gold@Silica Nanoparticles Functionalized with Oligonucleotides: A Prominent Tool for the Detection of the Methylated Reprimo Gene in Gastric Cancer by Dynamic Light Scattering Nanomaterials

Marchant MJ, Guzmán L, Corvalán AH, Kogan MJ

The Phylogeographic Diversity of EBV and Admixed Ancestry in the Americas⁻Another Model of Disrupted Human-Pathogen Co-Evolution. Cancers

Corvalán AH, Ruedlinger J, de Mayo T, Polakovicova I, Gonzalez-Hormazabal P, Aguayo F

A Novel Role for Helicobacter pylori Gamma-Glutamyltranspeptidase in Regulating Autophagy and Bacterial Internalization in Human Gastric Cells. Cancers

AC-AQ Bravo J, Díaz P, Corvalán AH, Quest AFG.

Using plasma cell-free DNA to monitor the chemoradiotherapy course of cervical cancer Int J Cancer

Tian J, Geng Y, Lv D, Li P, Cordova M, Liao Y, Tian X, Zhang X, Zhang Q, Zou K, Zhang Y, Zhang X, Li Y, Zhang J, Ma Z, Shao Y, Song L, Owen GI, Li T, Liu R, Liu Q, Zou L, Zhang Z, Li Z2

Targeted deep sequencing from multiple sources demostrates increased NOTCH1 alterations in lung cancer patient plasma Cancer Med

Liao Y1, Ma Z, Zhang Y, Li D, Lv D, Chen Z, Li P, Ai-Dherasi A, Zheng F, Tian J, Zou K, Wang Y, Wang D, Cordova M, Zhou H, Li X, Liu D, Yu R, Zhang X, Zhang J, Zhang X, Zhang X, Li Y, Shao Y, Song L, Liu R, Wang Y, Sufiyan S, Liu Q, Owen GI, Li Z, Chen J2

The Reprimo gene family member, reprimo-like (rprml), is requerid for blood development in embryonic zebrafish Scientific Reports

Stanic K, Reig G, Wichmann IA, Opazo JC, Owen GI, Corvalán AH, Concha ML, Amigo JD.

Identification of c.1531C>T Pathogenic Variant in the CDH1 Gene as a Novel Germline Mutation of Hereditary Diffuse Gastric Cancer Int. J. Mol. Sci.

Norero E, Alarcon MA, Hakkaart C, de Mayo T, Mellado C, Garrido M, Aguayo G, Lagos M, Torres J, Calvo A, Guilford P, Corvalan AH

Integrated Analysis of Mouse and Human Gastric Neoplasms Identifies Conserved microRNA Networks in Gastric Carcinogenesis. Gastroenterology

Zheng Chen1, Zheng Li, Mohammed Soutto, Weizhi Wang, M. Blanca Piazuelo, Shoumin Zhu, Yan Guo, Maria J. Maturana, Alejandro H. Corvalan, Xi Chen, Zekuan Xu and Wael M. El-Rifai

Fact or Fiction, It Is Time for a Verdict on Vasculogenic Mimicry? Frontiers in Oncology

Valdivia A, Mingo G, Aldana V, Pinto MP, Ramirez M, Retamal C, Gonzalez A, Nualart F, Corvalan AH, Owen G

High Proportion of Potential Candidates for Immunotherapy in a Chilean Cohort of Gastric Cancer Patients: Results of the FORCE1 Study Cancers

Cordova Delgado M, Pinto MP, Retamal IN, Muñoz Medel M, Bravo ML, Fernández MF, Cisternas B, Mondaca S, Sanchez C, Galindo H, Nervi B, Ibáñez C, Acevedo F, Madrid J, Peña J, Koch E, Maturana MJ, Romero D, de la Jara N, Torres J, Espinoza M, Balmaceda C, Liao Y, Li Z, Freire M, Gárate Calderón V, Cáceres J, Sepúlveda-Hermosilla G, Lizana R, Ramos L, Artigas R, Norero E, Crovari F, Armisén R, Corvalán AH, Owen GI, Garrido M2.

Epigenetic regulation of AURKA by miR-4715-3p in upper gastrointestinal cancers. Scientific Reports

Gomaa A, Peng D, Chen Z, Soutto M, Abouelezz K, Corvalan A, El-Rifai W2.

Chilean Registry for Neuroendocrine Tumors: A Latin American Perspective. Hormones & Cancer

Pinto MP, Muñoz Medel M, Carrillo D, Retamal IN, Bravo ML, Valenzuela Y, Nervi B, Sánchez C, Galindo H, Ibañez C, Peña J, Balmaceda C, Madrid J, Briones J, Torres J, Nilo F, Guarda FJ, Quintana JC, Orellana P, Mondaca S, Acevedo F, Vicentini D, Cordova Delgado M, Owen GI, Garrido M

CK2 inhibition with silmitasertib promotes methuosis-like cell death associated to catastrophic massive vacuolization of colorectal cancer cells. Cell death & disease

Silva Pavez E, Villar P, Trigo C, Caamaño E, Niechi I, Pérez P, Muñoz JP, Aguayo F, Burzio VA, Varas Godoy M, Castro AF, Colombo MI, Tapia JC.

Photothermally Controlled Methotrexate Release System Using ß-Cyclodextrin and Gold Nanoparticles Nanomaterials

Silva N, Riveros A, Yutronic N, Lang E, Chornik B, Guerrero S, Samitier J, Jara P, Kogan MJ.

Intranasal delivery of mesenchymal stem cell-derived exosomes reduces oxidative stress and markedly inhibits ethanol consumption and post-deprivation relapse drinking. Addict Biol.

Ezquer F, Quintanilla ME, Morales P, Santapau D, Ezquer M, Kogan MJ, Salas Huenuleo E, Herrera Marschitz M, Israel Y.

HAI Peptide and Backbone Analogs-Validation and Enhancement of Biostability and Bioactivity of BBB Shuttles Sci Rep

Arranz Gibert P, Prades R, Guixer B, Guerrero S, Araya E, Ciudad S, Kogan MJ, Giralt E, Teixidó M

Finding key nanoprecipitation variables for achieving uniform polymeric nanoparticles using neurofuzzy logic technology Drug Deliv Transl Res

Jara MO, Catalan Figueroa J, Landin M, Morales JO

A simple and green methodology to assemble poly (4-vinylpyridine) and a sulfonated azo-dye for obtaining stable polymeric nanoparticles Polymer

Catalán Toledo J, Nenen A, Vallejos GA, Oyarzun Ampuero F, Shibue T, Nishide H, Moreno-Villoslada

A mechanistic approach for the optimization of loperamide loaded nanocarriers characterization: Diafiltration and mathematical modeling advantages. Eur J Pharm Sci.

Catalan Figueroa J, Boisset CB, Jara MO, Flores ME, Moreno Villoslada I, Fiedler JL, Morales JO