Publicaciones

Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER-mitochondria communication during the early phase of ER stress. Cell Death Differ

Bravo Sagua R, Parra V, Ortiz Sandoval C, Navarro Marquez M, Rodríguez AE, Diaz Valdivia N, Sanhueza C, Lopez Crisosto C, Tahbaz N, Rothermel BA, Hill JA, Cifuentes M, Simmen T, Quest AFG, Lavandero S.

«Variability in Genomic and Virulent Properties of Porphyromonas gingivalis Strains Isolated From Healthy and Severe Chronic Periodontitis Individuals» Frontiers in Cellular and Infection Microbiology

Mendez K., Hoare A., Soto C., Buguelo I., Olivera M., Meneses C., Pérez-Donoso JM., Castro-Nallar E., Bravo D

The Netrin-4/Laminin γ1/Neogenin-1 complex mediates migration in SK-N-SH neuroblastoma cells Cell Adh Migr

Villanueva, A., Puvogel, S., Lois, P., Muñoz, E., Ramírez, M., Lubieniecki, F., Casco, F., Gallegos, I., García, J., Sanchez-Gomez, P., Torres V.A., Palma V.

Coagulation Factor Xa Promotes Solid Tumor Growth, Experimental Metastasis and Endothelial Cell Activation. Cancers

Arce M, Pinto MP, Galleguillos M, Muñoz C, Lange S, Ramirez C, Erices R, Gonzalez P, Velasquez E, Tempio F, Lopez MN, Salazar Onfray F, Cautivo K, Kalergis AM, Cruz S, Lladser Á, Lobos González L, Valenzuela G, Olivares N, Sáez C, Koning T, Sánchez FA, Fuenzalida P, Godoy A, Contreras Orellana P, Leyton L, Lugano R, Dimberg A, Quest AFG, Owen GI.

Role of glycosylation in hypoxia-driven cell migration and invasion Cell Adh Migr

Arriagada C, Silva P, Torres V.A.

Nuclear localization of β-catenin and expression of target genes are associated with increased Wnt secretion in oral dysplasia. Oral Oncol

Reyes M, Peña Oyarzún D, Maturana, A. Torres V.A

The Helicobacter pylori Urease Virulence Factor Is Required for the Induction of Hypoxia-Induced Factor-1α in Gastric Cells. Cancers

Valenzuela Valderrama M, Cerda Opazo P, Backert S, González MF, Carrasco Véliz N, Jorquera Cordero C, Wehinger S, Canales J, Bravo D, Quest AFG.

Focal adhesion kinase-dependent activation of the early endocytic protein Rab5 is associated with cell migration. J Biol Chem

Arriagada, C., Silva, P., Millet, M., Solano, L., Moraga, C. & Torres, V.A.

Chronic Inflammation as a Link between Periodontitis and Carcinogenesis Mediators Inflamm.

Hoare A, Soto C, Rojas V, Bravo D

Histatin-1 counteracts the cytotoxic and antimigratory effects of zoledronic acid in endothelial and osteoblast-like cells J Periodontol

Castro, M., Torres, P., Solano, L., Córdova, L. & Torres, V.A.

Cell Intrinsic and Extrinsic Mechanisms of Caveolin-1-Enhanced Metastasis. Biomolecules.

Campos A, Burgos Ravanal R, González MF, Huilcaman R, Lobos González L, Quest AFG.

Gold@Silica Nanoparticles Functionalized with Oligonucleotides: A Prominent Tool for the Detection of the Methylated Reprimo Gene in Gastric Cancer by Dynamic Light Scattering Nanomaterials

Marchant MJ, Guzmán L, Corvalán AH, Kogan MJ

The Phylogeographic Diversity of EBV and Admixed Ancestry in the Americas⁻Another Model of Disrupted Human-Pathogen Co-Evolution. Cancers

Corvalán AH, Ruedlinger J, de Mayo T, Polakovicova I, Gonzalez-Hormazabal P, Aguayo F

A Novel Role for Helicobacter pylori Gamma-Glutamyltranspeptidase in Regulating Autophagy and Bacterial Internalization in Human Gastric Cells. Cancers

AC-AQ Bravo J, Díaz P, Corvalán AH, Quest AFG.

Using plasma cell-free DNA to monitor the chemoradiotherapy course of cervical cancer Int J Cancer

Tian J, Geng Y, Lv D, Li P, Cordova M, Liao Y, Tian X, Zhang X, Zhang Q, Zou K, Zhang Y, Zhang X, Li Y, Zhang J, Ma Z, Shao Y, Song L, Owen GI, Li T, Liu R, Liu Q, Zou L, Zhang Z, Li Z2

Targeted deep sequencing from multiple sources demostrates increased NOTCH1 alterations in lung cancer patient plasma Cancer Med

Liao Y1, Ma Z, Zhang Y, Li D, Lv D, Chen Z, Li P, Ai-Dherasi A, Zheng F, Tian J, Zou K, Wang Y, Wang D, Cordova M, Zhou H, Li X, Liu D, Yu R, Zhang X, Zhang J, Zhang X, Zhang X, Li Y, Shao Y, Song L, Liu R, Wang Y, Sufiyan S, Liu Q, Owen GI, Li Z, Chen J2

The Reprimo gene family member, reprimo-like (rprml), is requerid for blood development in embryonic zebrafish Scientific Reports

Stanic K, Reig G, Wichmann IA, Opazo JC, Owen GI, Corvalán AH, Concha ML, Amigo JD.

Identification of c.1531C>T Pathogenic Variant in the CDH1 Gene as a Novel Germline Mutation of Hereditary Diffuse Gastric Cancer Int. J. Mol. Sci.

Norero E, Alarcon MA, Hakkaart C, de Mayo T, Mellado C, Garrido M, Aguayo G, Lagos M, Torres J, Calvo A, Guilford P, Corvalan AH

Integrated Analysis of Mouse and Human Gastric Neoplasms Identifies Conserved microRNA Networks in Gastric Carcinogenesis. Gastroenterology

Zheng Chen1, Zheng Li, Mohammed Soutto, Weizhi Wang, M. Blanca Piazuelo, Shoumin Zhu, Yan Guo, Maria J. Maturana, Alejandro H. Corvalan, Xi Chen, Zekuan Xu and Wael M. El-Rifai

Fact or Fiction, It Is Time for a Verdict on Vasculogenic Mimicry? Frontiers in Oncology

Valdivia A, Mingo G, Aldana V, Pinto MP, Ramirez M, Retamal C, Gonzalez A, Nualart F, Corvalan AH, Owen G

High Proportion of Potential Candidates for Immunotherapy in a Chilean Cohort of Gastric Cancer Patients: Results of the FORCE1 Study Cancers

Cordova Delgado M, Pinto MP, Retamal IN, Muñoz Medel M, Bravo ML, Fernández MF, Cisternas B, Mondaca S, Sanchez C, Galindo H, Nervi B, Ibáñez C, Acevedo F, Madrid J, Peña J, Koch E, Maturana MJ, Romero D, de la Jara N, Torres J, Espinoza M, Balmaceda C, Liao Y, Li Z, Freire M, Gárate Calderón V, Cáceres J, Sepúlveda-Hermosilla G, Lizana R, Ramos L, Artigas R, Norero E, Crovari F, Armisén R, Corvalán AH, Owen GI, Garrido M2.

Epigenetic regulation of AURKA by miR-4715-3p in upper gastrointestinal cancers. Scientific Reports

Gomaa A, Peng D, Chen Z, Soutto M, Abouelezz K, Corvalan A, El-Rifai W2.

Chilean Registry for Neuroendocrine Tumors: A Latin American Perspective. Hormones & Cancer

Pinto MP, Muñoz Medel M, Carrillo D, Retamal IN, Bravo ML, Valenzuela Y, Nervi B, Sánchez C, Galindo H, Ibañez C, Peña J, Balmaceda C, Madrid J, Briones J, Torres J, Nilo F, Guarda FJ, Quintana JC, Orellana P, Mondaca S, Acevedo F, Vicentini D, Cordova Delgado M, Owen GI, Garrido M

CK2 inhibition with silmitasertib promotes methuosis-like cell death associated to catastrophic massive vacuolization of colorectal cancer cells. Cell death & disease

Silva Pavez E, Villar P, Trigo C, Caamaño E, Niechi I, Pérez P, Muñoz JP, Aguayo F, Burzio VA, Varas Godoy M, Castro AF, Colombo MI, Tapia JC.

Photothermally Controlled Methotrexate Release System Using ß-Cyclodextrin and Gold Nanoparticles Nanomaterials

Silva N, Riveros A, Yutronic N, Lang E, Chornik B, Guerrero S, Samitier J, Jara P, Kogan MJ.

Intranasal delivery of mesenchymal stem cell-derived exosomes reduces oxidative stress and markedly inhibits ethanol consumption and post-deprivation relapse drinking. Addict Biol.

Ezquer F, Quintanilla ME, Morales P, Santapau D, Ezquer M, Kogan MJ, Salas Huenuleo E, Herrera Marschitz M, Israel Y.

HAI Peptide and Backbone Analogs-Validation and Enhancement of Biostability and Bioactivity of BBB Shuttles Sci Rep

Arranz Gibert P, Prades R, Guixer B, Guerrero S, Araya E, Ciudad S, Kogan MJ, Giralt E, Teixidó M

Finding key nanoprecipitation variables for achieving uniform polymeric nanoparticles using neurofuzzy logic technology Drug Deliv Transl Res

Jara MO, Catalan Figueroa J, Landin M, Morales JO

A simple and green methodology to assemble poly (4-vinylpyridine) and a sulfonated azo-dye for obtaining stable polymeric nanoparticles Polymer

Catalán Toledo J, Nenen A, Vallejos GA, Oyarzun Ampuero F, Shibue T, Nishide H, Moreno-Villoslada

A mechanistic approach for the optimization of loperamide loaded nanocarriers characterization: Diafiltration and mathematical modeling advantages. Eur J Pharm Sci.

Catalan Figueroa J, Boisset CB, Jara MO, Flores ME, Moreno Villoslada I, Fiedler JL, Morales JO

New strategies for the prevention and control of cervical cancer in Chile Salud Public Mex

Ferreccio C

Distribution of dysplasia and cancer in the gallbladder: an analysis from a high cancer-risk population Human Pathology

Koshiol J, Bellolio E, Vivallo C, Cook P, Roa JC, McGee EE, Losada H, Van Dyke AL, Van De Wyngard V, Prado R, Villaseca M, Riquelme P, Acevedo J, Olivo V, Pettit K, Hildesheim A, Medina K, Memis B, Adsay V, Ferreccio C, Araya JC

Association between ideal cardiovascular health and markers of subclinical cardiovascular disease Clin Cardiol

Shpilsky D, Bambs C, Kip K, Patel S, Aiyer A, Olafiranye O, Reis SE, Erqou S

Curcumin-loaded nanoemulsion: a new safe and effective formulation to prevent tumor reincidence and metastasis. Nanoscale

Guerrero S, Inostroza Riquelme M, Contreras Orellana P, Diaz Garcia V, Lara P, Vivanco Palma A, Cárdenas A, Miranda V, Robert P, Leyton L, Kogan MJ, Quest AFG, Oyarzun Ampuero F.

Tobacco Exposure Enhances Human Papillomavirus 16 Oncogene Expression via EGFR/PI3K/Akt/c-Jun Signaling Pathway in Cervical Cancer Cells Frontiers in Microbiology

Muñoz JP, Carrillo Beltrán D, Aedo Aguilera V, Calaf GM, León O, Maldonado E, Tapia JC, Boccardo E, Ozbun MA, Aguayo F

«Vasodilator and hypotensive effects of pure compounds and hydroalcoholic extract of Xenophyllum poposum (Phil) V.A Funk (Compositae) on rats» Phytomedicine

Cifuentes F, Palacios J, Kuzmicic J, Carvajal L, Muñoz F, Quispe C, Nwokocha CR, Morales G, Norambuena-Soto I, Chiong M, Paredes A.

StructRNAfinder: an automated pipeline and web server for RNA families prediction BMC Bioinformatics

Arias Carrasco R, Vásquez Morán Y, Nakaya HI, Maracaja Coutinho V

IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice. Biochim Biophys Acta Mol Basis Dis.

Valladares D, Utreras Mendoza Y, Campos C, Morales C, Diaz Vegas A, Contreras Ferrat A, Westermeier F, Jaimovich E, Marchi S, Pinton P, Lavandero S.

Heart Disease and Cancer: Are the Two Killers Colluding? Circulation.

Kitsis RN, Riquelme JA, Lavandero S.

Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci Genome Biology

Amaral PP, Leonardi T, Han N, Viré E, Gascoigne DK, Arias Carrasco R, Büscher M, Pandolfini L, Zhang A, Pluchino S, Maracaja Coutinho V, Nakaya HI, Hemberg M, Shiekhattar R , Enright AJ, Kouzarides T

CEMiTool: a Bioconductor package for performing comprehensive modular co-expression analyses BMC Bioinformatics

Russo PST, Ferreira GR, Cardozo LE, Bürger MC, Arias Carrasco R, Maruyama SR, Hirata TDC, Lima DS, Passos FM, Fukutani KF, Melissa Lever M, Silva JS, Maracaja-Coutinho V, Nakaya H

Autophagy mediates calcium-sensing receptor-induced TNFα production in human preadipocytes. Biochim Biophys Acta Mol Basis Dis

Mattar P, Bravo-Sagua R, Tobar N, Fuentes C, Troncoso R, Breitwieser G, Lavandero S, Cifuentes M.

Potential adverse cardiac remodelling in highly trained athletes: still unknown clinical significance. Eur J Sport Sci

Gabrielli L, Sitges M, Chiong M, Jalil J, Ocaranza M, Llevaneras S, Herrera S, Fernandez R, Saavedra R, Yañez F, Vergara L, Diaz A, Lavandero S, Castro P

Protection of the myocardium against ischemia/reperfusion injury by angiotensin-(1-9) through an AT2R and Akt-dependent mechanism Pharmacol Res.

Evelyn Mendoza Torresa, Jaime A. Riquelme, Alejandra Vielma, Andrea Ramirez Sagredo, Luigi Gabrielli, Roberto Bravo Sagua, Jorge E. Jalil, Beverly A. Rothermel, Gina Sanchez, Maria Paz Ocaranza, Sergio Lavandero

Increased active phase atrial contraction is related to marathon runner performance European Journal of Applied Physiolog

Luigi Gabrielli, Sebastián Herrera, Felipe Contreras Briceño, Julián Vega, María Paz Ocaranza, Fernando Yáñez, Rodrigo Fernández, Rodrigo Saavedra, Marta Sitges, Lorena García, Mario Chiong, Sergio Lavandero, Pablo F. Castro

Angiotensin-(1-9) reduces cardiovascular and renal inflammation in experimental renin-independent hypertension. Biochem Pharmacol

Gonzalez L, Novoa U, Moya J, Gabrielli L, Jalil JE, García L, Chiong M, Lavandero S, Ocaranza MP.

Nanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: evolution toward prospective theranostic approaches. Theranostics.

Bejarano J, Navarro Marquez M, Morales Zavala F, Morales JO, Garcia Carvajal I, Araya Fuentes E, Flores Y, Verdejo HE, Castro PF, Lavandero S, Kogan MJ

Totally Organic Redox-Active pH-Sensitive Nanoparticles Stabilized by Amphiphilic Aromatic Polyketones J Phys Chem B

Araya Hermosilla E, Catalan Toledo J, Muñoz Suescun F, Oyarzun Ampuero F, Raffa P, Polgar LM, Picchioni F, Moreno Villoslada

The Effect of Inkjet Printing over Polymeric Films as Potential Buccal Biologics Delivery Systems. AAPS PharmSciTech

Montenegro Nicolini M, Reyes PE, Jara MO, Vuddanda PR, Neira-Carrillo A, Butto N, Velaga S, Morales JO

The antinociceptive effect of resveratrol in bone cancer pain is inhibited by the Silent Information Regulator 1 inhibitor selisistat J Pharm Pharmacol

Lux S, Lobos N, Lespay-Rebolledo C, Salas-Huenuleo E, Kogan MJ, Flores C, Pinto M, Hernandez A, Pelissier T, Constandil L

Stability of Antibacterial Silver Carboxylate Complexes against Staphylococcus epidermidis and Their Cytotoxic Effects. Molecules

Aldabaldetrecu M, Tamayo L, Alarcon R, Walter M, Salas-Huenuleo E, Kogan MJ, Guerrero J, Paez M, Azocar MI

Label-Free Graphene Oxide-Based Surface Plasmon Resonance Immunosensor for the Quantification of Galectin-3, a Novel Cardiac Biomarker ACS Appl Mater Interfaces

Primo EN, Kogan MJ, Verdejo HE, Bollo S, Rubianes MD, Rivas GA.

Protection of astaxanthin from photodegradation by its inclusion in hierarchically assembled nano and microstructures with potential as food Food Hydrocolloids

Alarcón Alarcón C, Inostroza Riquelme M, Torres Gallegos C, Araya C, Miranda M, Sánchez Caamaño JC, Moreno Villoslada I2, Oyarzun Ampuero F

Porous Nanogold/Polyurethane Scaffolds with Improved Antibiofilm, Mechanical, and Thermal Properties and with Reduced Effects on Cell Viability: A Suitable Material for Soft Tissue Applications ACS Appl Mater Interfaces

Tamayo L, Acuña D, Riveros AL, Kogan MJ, Azócar MI, Páez M, Leal M, Urzúa M, Cerda E.

Peptide functionalized magneto-plasmonic nanoparticles obtained by microfluidics for inhibition of ß-amyloid aggregation Journal of Materials Chemistry B

Hassan N, Cordero ML, Sierpe R, Almada M, Juárez J, Valdez M, Riveros A, Vargas E, Abou Hassan A, Rusoi JM, Kogan MJ

Gold nanorods/siRNA complex administration for knockdown of PARP-1: a potential treatment for perinatal asphyxia International Journal of Nanomedicine

Vio V, Riveros AL, Tapia Bustos A, Lespay Rebolledo C, Perez Lobos R, Muñoz L, Pismante P, Morales P, Araya E, Hassan N, Herrera Marschitz M, Kogan MJ

Functionalization of stable fluorescent nanodiamonds towards reliable detection of biomarkers for Alzheimer’s disease J Nanobiotechnology

Morales-Zavala F, Casanova-Morales N, Gonzalez RB, Chandia-Cristi A, Estrada LD, AlvizaI, Waselowski V, Guzman F, Guerrero S, Oyarzun Olave M, Rebolledo C, Rodriguez E, Armijo J, Bhuyan H, Favre M, Alvarez AR, Kogan MJ, Maze JR

Electrocatalytic Activity of Nanohybrids Based on Carbon Nanomaterials and MFe2O4 (M=Co, Mn) towards the Reduction of Hydrogen Peroxide Electroanalysis

Gutierrez FA, Mazario E, Menéndez N, Herrasti P, Rubianes MD, Zagal JH, Yañez C, Rivas GA, Bollo S, Recio FJ

Double emulsions as potential fat replacers with gallic acid and quercetin nanoemulsions in the aqueous phases Food Chem

Silva W, Torres Gatica MF, Oyarzun Ampuero F, Silva-Weiss A, Robert P, Cofrades S, Gimenez B

Co2SnO4/Carbon Nanotubes Composites: A Novel Approach for Electrochemical Sensing of Hydrogen Peroxide

Yedinak E, Venegas CJ, Brito TP, Ruiz-León D, Bollo S

CLPFFD–PEG functionalized NIR-absorbing hollow gold nanospheres and gold nanorods inhibit ß-amyloid aggregation

Ruff J, Hassan N, Morales-Zavala F, Steitz J, Araya E, Kogan MJ, Simon U

Chitosan/chondroitin sulfate aerogels with high polymeric electroneutralization degree: formation and mechanical properties

Orellana SL, Giacaman A, Vidal A, Morales C, Oyarzun-Ampuero F, Lisoni JG, Henríquez-Báez C, Morán-Trujillo L, Concha M, Moreno-Villoslada I

Carboxymethylcellulose from bleached organosolv fibers of Eucalyptus nitens: synthesis and physicochemical characterization

Yáñez-S M, Matsuhiro B, Maldonado S, González R, Luengo J, Uyarte O, Serafine D, Moya S, Romero J, Torres R, Kogan MJ

Antibacterial activity against Staphylococcus aureus of chitosan/chondroitin sulfate nanocomplex aerogels alone and enriched with erythromycin and elephant garlic (Allium ampeloprasum L. var. ampeloprasum) extract

Gómez MA, Bonilla JM, Coronel MA, Martínez J, Morán-Trujillo L, Orellana SL, Vidal A, Giacaman A, Morales C, Torres-Gallegos C, Concha M, Oyarzun-Ampuero F, Godoy P, Lisoni JG, Henríquez-Báez C, Bustos C, Moreno-Villoslada I

Typhoid Fever in Chile 1969-2012: Analysis of an Epidemic and Its Control

Marco C, Delgado I, Vargas C, Muñoz X, Bhutta ZA, Ferreccio C

Obesity and increased susceptibility to arsenic-related type 2 diabetes in Northern Chile

Castriota F, Acevedo J, Ferreccio C, Smith AH, Liaw J, Smith MT, Steinmaus C

Neurological soft signs as a marker of cognitive impairment severity in people living with HIV

Toro P, Ceballos ME, Pesenti J, Inostroza M, Valenzuela D, Henríquez F, Forno G, Herold C, Schröder J, Calderón

Age at Exposure to Arsenic in Water and Mortality 30–40 Years After Exposure Cessation

Roh T, Steinmaus C, Marshall G, Ferreccio C, Liaw J, Smith AH

Gold nanoparticles as tracking devices to shed light on the role of caveolin-1 in early stages of melanoma metastasis

Guerrero S, Diaz Garcia VM, Contreras Orellana P, Lara P, Palma S, Guzman F, Lobos Gonzalez L, Cardenas A, Rojas Silva X, Muñoz L, Leyton L, Kogan MJ, Quest AF

Autophagy and oxidative stress in non-communicable diseases: A matter of the inflammatory state?

Peña Oyarzun D, BravoSagua R, Diaz-Vega A, Aleman L, Chiong M, Garcia L, Bambs C, Troncoso R, Cifuentes M, Morselli E, Ferreccio C, Quest AFG, Criollo A, Lavandero S

Biomimetic quantum dot-labeled B16F10 murine melanoma cells as a tool to monitor early steps of lung metastasis by in vivo imaging

Díaz-García VM, Guerrero S, Díaz-Valdivia N, Lobos-González L, Kogan M, Pérez-Donoso JM, Quest AF

Metformin prevents nerve growth factor-dependent proliferative and proangiogenic effects in epithelial ovarian cancer cells and endothelial cells

Garrido MP, Vera C, Vega M, Quest AFG, Romero C

Intracellular Ca2+ Increases and Connexin 43 Hemichannel Opening Are Necessary but Not Sufficient for Thy-1-Induced Astrocyte Migration

Raúl Lagos-Cabré, Marianne Brenet, Jorge Díaz, Ramón D. Pérez, Leonardo A. Pérez, Rodrigo Herrera-Molina, Andrew FG Quest y Lisette Leyton

J Castillo Bennett, P Silva, S Martínez, VA Torres, AFG Quest

J Castillo Bennett, P Silva, S Martínez, VA Torres,  AFG Quest

Helicobacter pylori in human health and disease: Mechanisms for local gastric and systemic effects.

Denisse Bravo , Anilei Hoare , Cristopher Soto , Manuel A Valenzuela y Andrew FG Quest

Helicobacter pylori and Gastric Cancer: Adaptive Cellular Mechanisms Involved in Disease Progression

Paula Díaz, Manuel Valenzuela Valderrama, Jimena Bravo y Andrew FG Quest

Caveolin-1-containing extracellular vesicles transport adhesion proteins and promote malignancy in breast cancer cell lines

América Campos, Carlos Salomon, Rocío Bustos, Jorge Díaz, Samuel Martínez, Verónica Silva, Constanza Reyes, Natalia Díaz-Valdivia, Manuel Varas-Godoy, Lorena Lobos-González, Andrew F

Association of high 5-hydroxymethylcytosine levels with Ten Eleven Translocation 2 overexpression and inflammation in Sjögren’s syndrome patients

Carolina Lagos, Patricia Carvajal, Isabel Castro, Daniela Jara,  Sergio González,  Sergio Aguilera,  María-José Barrera,  Andrew FG,  Bahamondes Verónica,  Claudio Molina ,  Ulises Urzúa, Marcela A Hermoso, Cecilia Leyton, María-Julieta González

The Reprimo Gene Family: A Novel Gene Lineage in Gastric Cancer with Tumor Suppressive Properties

Julio D. Amigo, Juan C, Opazo, Roddy Jorquera, Ignacio A. Wichmann, Benjamin A. García, Maria Alejandra Alarcon, Gareth I. Owen y Alejandro H. Corvalán 3

Simvastatin interferes with cancer ‘stem-cell’plasticity reducing metastasis in ovarian cancer

S Kato , MF Liberona, J Cerda-Infante, M Sánchez, J Henríquez, C Bizama, ML Bravo, P Gonzalez, R Gejman, J Brañes, K García, C Ibañez, GI Owen, JC Roa, V Montecinos y MA Cuello

Patient inflammatory status and CD4+/CD8+ intraepithelial tumor lymphocyte infiltration are predictors of outcomes in high-grade serous ovarian cancer.

Mauricio P. Pinto a Carlos Balmaceda b Maria L. Bravo a c Sumie Kato d Alejandra Villarroel e Gareth I. Owen c f Juan Carlos Roa e Mauricio A. Cuello d Carolina Ibañez

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Théry C, Witwer KW, Aikawa, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC1, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A

Conflicts of CpG density and DNA methylation are proximally and distally involved in gene regulation in human and mouse tissues

Chen F, Zhang Q, Deng X, Zhang X, Chen C, Lv D, Li Y, Li D, Zhang Y, Li P, Diao Y, Kang L, Owen GI, Chen J, Li Z2.

Chilean Gastric Cancer Task Force: A study protocol to obtaoin a clinical and molecular classification of a cohort of gastric cancer patients

Gareth Owen; Mauricio Pinto; Ignacio Retamal; María Fernádez; Betzabe Cisternas; Sebastian Mondaca; Cesar Sanchez; Hector Galindo; Bruno Nervi; Carolina Ibañez; Francisco Acevedo; Jorge Madrid; José Peña; Maria Bravo; Maria Maturana; Miguel Cordova-Delgado; Diego Romero; Nathaly de la Jara; Javiera Torres; Maria Rodriguez-Fernandez; Manuel Espinoza; Carlos Balmaceda; Matías Freire; Valentina Gárate-Calderón; Fernando Crovari; Paula Jimenez-Fonseca; Alberto Carmona-Bayonas; Ariel Zwenger; Ricardo Armisen; Alejandro Corvalan, Marcelo Garrido

Cardiotoxicidad inducida por tratamientos oncológicos. Fundamentos para la implementación de equipos de Cardio-Oncología

René Hameau, Luigi Gabrielli, Marcelo Garrido, Ana María Guzmán, Ignacio Retamal, María José Vacarezza, Douglas Greig, Mauricio Ocqueteau, César Sánchez, Marcela Pizarro, Alejandro Corvalán, Sergio Lavandero, Pablo F. Castro, Gonzalo Martínez

Encapsulation of Gold Nanostructures and Oil-in-Water Nanocarriers in Microgels with Biomedical Potential

Mariela Inostroza-Riquelme, Andrea Vivanco, Pablo Lara, Simón Guerrero, Edison Salas-Huenuleo, Alejandro Chamorro, Lisette Leyton, Karen Bolaños, Eyleen Araya, Andrew F G Quest, Marcelo J Kogan, Felipe Oyarzun-Ampuero

Inverse expression of survivin and reprimo correlates with poor patient prognosis in gastric cancer

Paulina Cerda-Opazo, Manuel Valenzuela-Valderrama, Ignacio Wichmann, Andrés Rodríguez, Daniel Contreras-Reyes, Elmer A. Fernández, Gonzalo Carrasco-Aviño, Alejandro H. Corvalán y Andrew FG Quest

Lysosomotropic bafilomycin-A1 and ML9 causes cell death without affecting the ROS and ATP level

Soni Shaikh, Suman K. Nandy, Carles Cantí, Sergio Lavandero

Impact of Estrogens and Estrogen Receptor Alpha (ESR1) in Brain Lipid Metabolism

Eugenia Morselli, Roberta de Souza Santos, Su Gao,  Yenniffer Ávalos,  Alfredo Criollo,  Biff F Palmer,  Deborah J Clegg

High-Fat-Diet-Induced Obesity Produces Spontaneous Ventricular Arrhythmias and Increases the Activity of Ryanodine Receptors in Mice.

Gina Sánchez, Felipe Araneda, Juan Pedro Peña, José Pablo Finkelstein, Jaime A Riquelme, Luis Montecinos, Genaro Barrientos, Llanos Paola, Zully Pedrozo, Dijo Matilde, Ricardo Toro, Paulina Donoso

Heparan sulfate potentiates leukocyte adhesion on cardiac fibroblast by enhancing Vcam-1 and Icam-1 expression

Francisco Olivares-Silva, Rodolfo Landaeta, Pablo Aránguiz, Samir Bolívar,  Claudio Humeres, Renatto Anfossi ,  Raúl Vivar,  Pía Boza,  Claudia Muñoz, Viviana Pardo-Jiménez,  Concepción Peiró,  Carlos F Sánchez-Ferrer,  Guillermo Díaz-Araya

Mechanical stretch increases L-type calcium channel stability in cardiomyocytes through a polycystin-1/AKT-dependent mechanism

A Córdova - Casanova, Me Olmedo, JA Riquelme, G Barrientos,  G Sánchez, TG Gillette,  S Lavandero,  M Chiong,  P Donoso,  Z Pedrozo

Polycystin-2-dependent control of cardiomyocyte autophagy

Alfredo Criollo,  Francisco Altamirano,  Zully Pedrozo,  Gabriele G Schiattarella,  Dan L Li,  Pablo Rivera-Mejías,  Cristian Sotomayor-Flores,  Valentina Parra,  Elisa Villalobos,  Pavan K Battiprolu,  Nan Jiang,  Eugenia Morselli,  Hernan L Mayo, Stefan Somlo,  Humbert de Smedt,  Thomas G Gillette,  Sergio Lavandero,  Joseph Una Colina.

Down Syndrome Critical Region 1 Gene, Rcan1, Helps Maintain a More Fused Mitochondrial Network

Valentina Parra,  Francisco Altamirano,  Carolina P Hernández-Fuentes,  Dan Tong ,  Victoriia Kyrychenko,  David Rotter,  Zully Pedrozo ,  Joseph Una Colina,  Verónica Eisner,  Sergio Lavandero,  Jay W Schneider,  Beverly A Rothermel.

The STIM1 inhibitor ML9 disrupts basal autophagy in cardiomyocytes by decreasing lysosome content

S Shaikh ,  R Troncoso ,  D Mondaca-Ruff,  V Parra,  L García,  M Chiong,  S Lavandero.

Cardioprotection mediated by exosomes is impaired in the setting of type II diabetes but can be rescued by the use of non-diabetic exosomes in vitro.

Sean M Davidson, Jaime A Riquelme, Kaloyan Takov, Jose M Vicencio, Claire Boi-Doku,  Vanessa Khoo , Cristiano Doreth,  Dina Radenkovic,  Sergio Lavandero,  Derek M Yellon.

Mifepristone enhances insulin-stimulated Akt phosphorylation and glucose uptake in skeletal muscle cells.

Izela Bernal-Dolor,  Mario Navarro-Márquez,  César Osorio-Fuentealba,  Francisco Díaz-Castro,  Andrea Del Campo,  Camila Donoso-Barraza,  Omar Porras,  Sergio Lavandero,  Rodrigo Troncoso.

«Gigantic» biatrial myxoma with right heart functional impairment.

Julián Vega Adauy, Luigi Gabrielli, Samuel Córdova, Paul McNab, Rodrigo Saavedra  Marta Piñeiro, Ricardo Zalaquett

A new role for HERPUD1 and ERAD activation in osteoblast differentiation and mineralization

Américo-Da-Silva, Luan; Diaz, Jheimmy; Bustamante, Mario; Mancilla, Georthan; Oyarzún, Ingrid; Verdejo, Hugo E.; Quiroga, Clara

Preparation of a novel lipid-core micelle using a low-energy emulsification method

Hans F. Fritz, Andrea C. Ortiz, Sitaram P. Velaga y Javier O. Morales.

Exploring the influence of Diels-Alder linker length on photothermal molecule release from gold nanorods.

Claudia Vetterlein, Rodrigo Vásquez, Karen Bolaños, Gerardo A. Acosta, Fanny Guzman, Fernando Albericio, Freddy Celis, Marcelo Campos, Marcelo J. Kogan, Eyleen Araya.

Lung, Bladder, and Kidney Cancer Mortality 40 Years After Arsenic Exposure Reduction.

Allan H Smith, Guillermo Marshall, Taehyun Roh, Catterina Ferreccio, Jane Liaw, Craig Steinmaus.

Impaired IRE1/XBP-1 pathway associated to DNA methylation might contribute to salivary gland dysfunction in Sjögren’s syndrome patients.

Denisse Sepúlveda, María-José Barrera, Isabel Castro,  Sergio Aguilera,  Patricia Carvajal, Carolina Lagos, Sergio González,  Nicolás Albornoz, Verónica Bahamondes, Andrew FG Quest, Ulises Urzúa, Claudio Molina, Cecilia Leyton, Marcela A Hermoso, María-Julieta González.

Single-molecule force spectroscopy measurement of Thy-1/avb3-integrin interaction using non-purified proteins

Francesca Burgos-Bravo, Nataniel L. Figueroa, Nathalie Casanova-Morales, Andrew FG Quest, Christian AM Wilsony Lisette Leyton.

Expression of RPRM/rprm in the Olfactory System of Embryonic Zebrafish (Danio rerio)

Karen Stanic, Alonso Quiroz, Carmen G. Lemus, Ignacio A. Wichmann, Alejandro H. Corvalán, Gareth I. Owen, Juan C. Opazo7, Miguel L. Concha and Julio D. Amigo1

Role of microRNAs and Exosomes in Helicobacter pylori and Epstein-Barr Virus Associated Gastric Cancers.

Iva Polakovicova, Sofía Jerez, Ignacio A. Wichmann, Alejandra Sandoval- Bórquez, Nicolás Carrasco-Véliz y Alejandro H. Corvalán.

Herpud1 impacts insulin-dependent glucose uptake in skeletal muscle cells by controlling the Ca 2+-calcineurin-Akt axis

Mario Navarro-Marquez , Natalia Torrealba, Rodrigo Troncoso, Cesar Vásquez-Trincado, Marcelo Rodriguez , Pablo E Morales, Elisa Villalobos, Yuka Eura, Lorena Garcia , Mario Chiong , Amira Klip, Enrique Jaimovich,  Koichi Kokame, Sergio Lavandero

Cardiotoxicidad inducida por tratamientos oncologicos. Fundamentos para la implementacion de equipos de Cardio-Oncologia

Hameau R , Gabrielli L , Garrido M , Guzman AM , Retamal I , Vacarezza MJ, Greig D, Ocqueteau M , Sanchez C, Pizarro M, Corvalan AH, Lavandero S, Castro PF, Martinez G

Encapsulation of Gold Nanostructures and Oil-in-Water Nanocarriers in Microgels with Biomedical Potential

Inostroza-Riquelme M , Vivanco A, Lara P, Guerrero S, Salas-Huenuleo E, Chamorro A, Leyton L, Bolanos K, Araya E, Quest AFG, Kogan MJ, Oyarzun-Ampuero F

Inverse expression of survivin and reprimo correlates with poor patient prognosis in gastric cancer

Cerda-Opazo P , Valenzuela-Valderrama M,  Wichmann I, Rodriguez A, Contreras-Reyes D , Fernandez EA,  Carrasco-Avino G ,  Corvalan AH , Quest AFG .

P-345 – Lysosomotropic bafilomycin-A1 and ML9 causes cell death without affecting the ROS and ATP level

Shaikh S , Suman KN, Canti C, Lavandero S

Impact of Estrogens and Estrogen Receptor Alpha (ESR1) in Brain Lipid Metabolism

Morselli E , de Souza Santos R, Gao S, Avalos Y ,  Criollo A , Palmer BF, Clegg DJ.

High-Fat-Diet-Induced Obesity Produces Spontaneous Ventricular Arrhythmias and Increases the Activity of Ryanodine Receptors in Mice.

Sanchez G , Araneda F , Pena JP, Finkelstein JP, Riquelme JA , Montecinos L, Barrientos G, Llanos P,  Pedrozo Z , Said M, Bull R, Donoso P .

Heparan sulfate potentiates leukocyte adhesion on cardiac fibroblast by enhancing Vcam-1 and Icam-1 expression

Olivares-Silva F , Landaeta R, Aranguiz P, Bolivar S, Humeres C, Anfossi R , Vivar R, Boza P, Munoz C, Pardo-Jimenez V, Peiro C, Sanchez-Ferrer CF, Diaz-Araya G .

Herpud1 impacts insulin-dependent glucose uptake in skeletal muscle cells by controlling the Ca2+-calcineurin-Akt axis

Navarro-Marquez M , Torrealba N, Troncoso R, Vasquez-Trincado C, Rodriguez M, Morales PE, Villalobos E , Eura Y, Garcia L, Chiong M , Klip A, Jaimovich E, Kokame K, Lavandero S .

Mechanical stretch increases L-type calcium channel stability in cardiomyocytes through a polycystin-1/AKT-dependent mechanism

Cordova-Casanova A , Olmedo I, Riquelme J , Barrientos G, Sanchez G, Gillette TG, Lavandero S, Chiong M , Donoso P , Pedrozo Z

Polycystin-2-dependent control of cardiomyocyte autophagy

Criollo A , Altamirano F, Pedrozo Z , Schiattarella GG, Li DL, Rivera-Mejias P, Sotomayor-Flores C, Parra V, Villalobos E , Battiprolu PK, Jiang N, May HI, Morselli E, Somlo S, de Smedt H, Gillette TG, Lavandero S , Hill JA

Down Syndrome Critical Region 1 Gene, Rcan1, Helps Maintain a More Fused Mitochondrial Network

Parra V , Altamirano F, Hernandez-Fuentes CP , Tong D, Kyrychenko V, Rotter D,  Pedrozo Z , Hill JA, Eisner V,  Lavandero S , Schneider JW, Rothermel BA

The STIM1 inhibitor ML9 disrupts basal autophagy in cardiomyocytes by decreasing lysosome content

Shaikh S , Troncoso R, Mondaca-Ruff D, Parra V, Garcia L, Chiong M , Lavandero S

Cardioprotection mediated by exosomes is impaired in the setting of type II diabetes but can be rescued by the use of non-diabetic exosomes in vitro.

Davidson SM ,  Riquelme JA , Takov K, Vicencio JM, Boi-Doku C, Khoo V, Doreth C, Radenkovic D, Lavandero S , Yellon DM.

Mifepristone enhances insulin-stimulated Akt phosphorylation and glucose uptake in skeletal muscle cells.

Bernal-Sore I , Navarro-Marquez M, Osorio-Fuentealba C, Diaz-Castro F, Del Campo A, Donoso-Barraza C, Porras O, Lavandero S, Troncoso R

«Gigantic» biatrial myxoma with right heart functional impairment

Vega Adauy J , Gabrielli L , Cordova S, McNab P, Saavedra R, Pineiro M, Zalaquett R.

A new Role for HERPUD1 and ERAD activation in osteoblast differentation and mineralization.

Da Silva L , Diaz J, Bustamante M, Oyarzun I, Verdejo H, Quiroga C

Preparation of a novel lipid-core micelle using a low-energy emulsification method

Fritz HF ,  Ortiz AC , Velaga SP,  Morales JO

Exploring the influence of Diels-Alder linker length on photothermal molecule release from gold nanorods.

Vetterlein C , Vasquez R, Bolanos K, Acosta GA, Guzman F, Albericio F, Celis F, Campos M, Kogan MJ , Araya E

Lung, Bladder, and Kidney Cancer Mortality 40 Years After Arsenic Exposure Reduction.

Smith AH , Marshall G, Roh T, F erreccio C, Liaw J, Steinmaus C

Impaired IRE1/XBP-1 pathway associated to DNA methylation might contribute to salivary gland dysfunction in Sjogren’s syndrome patients.

Sepulveda D , Barrera MJ , Castro I , Aguilera S, Carvajal P, Lagos C, Gonzalez S, Albornoz N, Bahamondes V, Quest AFG, Urzua U, Molina C, Leyton C, Hermoso M, Gonzalez MJ

Single-molecule force spectroscopy measurement of Thy-1/avb3-integrin interaction using non-purified proteins

Burgos-Bravo F . Figueroa N, Casanova N, Quest AFG, Wilson CAM , Leyton L

Expression of RPRM/rprm in the Olfactory System of Embryonic Zebrafish (Danio rerio)

Stanic K , Quiroz A , Lemus CG , Wichmann IA ,  Corvalan AH ,  Owen GI , Opazo JC, Concha ML, Amigo JD .

Role of microRNAs and Exosomes in Helicobacter pylori and Epstein-Barr Virus Associated Gastric Cancers.

Polakovicova I , Jerez S, Wichmann IA, Sandoval-Borquez A, Carrasco-Veliz N,  Corvalan AH .

Novel Therapies Targeting Cardioprotection and Regeneration.

Garrido V , Mendoza-Torres E, Riquelme JA, Diaz A, Pizarro M, Bustamante M, Chavez MN, Ocaranza MP , Mellado R, Corbalan R, Allende ML, Lavandero S

Inhibition of mitochondrial fission prevents hypoxia-induced metabolic shift and cellular proliferation of pulmonary arterial smooth muscle cells.

Parra V , Bravo-Sagua R, Norambuena-Soto I, Hernandez-Fuentes CP, Gomez-Contreras AG, Verdejo HE, Mellado R, Chiong M, Lavandero S , Castro PF

Increased C-reactive protein plasma levels are not involved in the onset of post-operative atrial fibrillation.

Del Campo A , Roldan J , Verdejo HE, Zalaquett R, Becerra E, Navarro-Marquez M, Mellado R , Lavandero S, Corbalan R, Garcia L, Chiong M

Herpud1 negatively regulates pathological cardiac hypertrophy by inducing IP3 receptor degradation

Torrealba N , Navarro-Marquez M, Garrido V, Pedrozo Z, Romero D, Eura Y, Villalobos E, Roa JC, Chiong M, Kokame K , Lavandero S

Sarcoplasmic reticulum-mitochondria communication in cardiovascular pathophysiology

Lopez-Crisosto C , Pennanen C, Vasquez-Trincado C, Morales PE, Bravo-Sagua R, Quest AFG, Chiong M, Lavandero S

Calcium Transport and Signaling in Mitochondria.

Bravo-Sagua R , Parra V, Lopez-Crisosto C, Diaz P, Quest AFG, Lavandero S

Structural and functional identification of vasculogenic mimicry in vitro.

Racordon D , Valdivia A , Mingo G, Erices R, Aravena R, Santoro F, Bravo ML, Ramirez C, Gonzalez P,  Sandoval A , Gonzalez A, Retamal C,  Kogan MJ , Kato S, Cuello MA, Osorio G, Nualart F, Alvares P, Gago-Arias A, Fabri D, Espinoza I, Sanchez B,  Corvalan AH , Pinto MP,  Owen GI

MicroRNA-335-5p is a potential suppressor of metastasis and invasion in gastric cancer

Sandoval-Borquez A , Polakovicova I, Carrasco-Veliz N, Lobos-Gonzalez L , Riquelme I,  Carrasco-Avino G , Bizama C , Norero E, Owen GI, Roa JC, Corvalan AH

Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.

Weber H , Valbuena JR , Barbhuiya MA, Stein S, Kunkel H,  Garcia P, Bizama C , Riquelme I, Espinoza JA, Kurtz SE, Tyner JW, Calderon JF,  Corvalan AH , Grez M, Pandey A, Leal-Rojas P ,  Roa JC

The salivary peptide histatin-1 promotes endothelial cell adhesion, migration and angiogenesis

Torres P , Diaz J, Arce M , Silva P, Mendoza P, Lois P, Molina-Berrios, Owen GI , Palma V, Torres VA

Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression.

Erices R , Cubillos S, Aravena R, Santoro F, Marquez M, Orellana R, Ramirez C, Gonzalez P, Fuenzalida P, Bravo ML, Oliva B, Kato S, Ibanez C, Branes J, Bravo E, Alonso C, Garcia K, Arab C, Torres VA, Godoy AS, Pereira J, Bustos G, Cardenas JC, Cuello MA, Owen GI

Subcellular Remodeling of the T-Tubule Membrane System: The Limits of Myocardial Recovery Revealed?

Rame JE , Lavandero S

The role of PI3Kα isoform in cardioprotection.

Rossello X , Riquelme JA , He Z, Taferner S, Vanhaesebroeck B, Davidson SM, Yellon DM

Hyperosmotic stress stimulates autophagy via polycystin-2.

Pena-Oyarzun D , Troncoso R , Kretschmar C, Hernando C, Budini M, Morselli E, Lavandero S , Criollo A

Ca2+/Calmodulin-Dependent Protein Kinase II and Androgen Signaling Pathways Modulate MEF2 Activity in Testosterone-Induced Cardiac Myocyte Hypertrophy

Duran J , Lagos D, Pavez M, Troncoso MF, Ramos S, Barrientos G, Ibarra C, Lavandero S , Estrada M

The effect of oestrogens and their receptors on cardiometabolic health

Morselli E, Santos RS,  Criollo A , Nelson MD, Palmer BF, Clegg DJ

Mitochondria in Structural and Functional Cardiac Remodeling

Torrealba N , Aranguiz P, Alonso C, Rothermel BA , Lavandero S

Incidencia y letalidad intrahospitalaria por insuficiencia cardiaca en Chile: ¿Existen diferencias por sexo?

Diaz-Toro F , Nazzal C , Verdejo H. 

Gender influence on the adaptation of atrial performance to training.

Sanchis L , Sanz-De La Garza M, Bijnens B, Giraldeau G, Grazioli G, Marin J, Gabrielli L , Montserrat S, Sitges M.

Big thrombus «sitting» in an atrial septal aneurysm.

Adauy JV ,  Gabrielli L , Cordova S, Saavedra R, McNab P.

Immobilization of graphene-derived materials at gold surfaces: Towards a rational design of protein-based platforms for electrochemical and plasmonic applications

Primo EN , Bollo S , Rubianes MD , Rivas GA

Gold nanoparticles stabilized with ßcyclodextrin-2-amino-4-(4-chlorophenyl)thiazole complex: A novel system for drug transport

Asela I , Noyong M, Simon U, Andrades-Lagos J, Campanini-Salinas J, Vasquez-Velasquez D, Kogan MJ , Yutronic N , Sierpe R

Effect of diazotated sulphonated polystyrene films on the calcium oxalate crystallization

Vasquez-Quitral P , Toledo Arana J, Miras MC, Acevedo DF, Barbero CA, N eira-Carrillo A

Construction of 6-thioguanine and 6-mercaptopurine carriers based on βcyclodextrins and gold nanoparticles

Sierpe R , Noyong M, Simon U, Aguayo D, Huerta J,  Kogan MJ , Yutronic N

Improving gold nanorod delivery to the central nervous system by conjugation to the shuttle Angiopep-2

Velasco-Aguirre C, Morales-Zavala F, Salas-Huenuleo E, Gallardo-Toledo E , Andonie O , Munoz L, Rojas X, Acosta G, Sanchez-Navarro M, Giralt E, Araya E, Albericio F ,  Kogan MJ

Peptide multifunctionalized gold nanorods decrease toxicity of β-amyloid peptide in a Caenorhabditis elegans model of Alzheimer’s disease

Morales-Zavala F , Arriagada H, Hassan N,  Velasco C, Riveros A , Alvarez AR, Minniti AN, Rojas-Silva X, Munoz LL, Vasquez R, Rodriguez K, Sanchez-Navarro M, Giralt E, Araya E, Aldunate R,  Kogan MJ

Gold nanoparticles as an efficient drug delivery system for GLP-1 peptides

Perez-Ortiz M , Zapata-Urzua C, Acosta GA, Alvarez-Lueje A , Albericio F , Kogan MJ

Buccal delivery of small molecules and biologics: of mucoadhesive polymers, films, and nanoparticles.

Morales JO , Brayden DJ

Effect of surfactants and drug load on physico-mechanical and dissolution properties of nanocrystalline tadalafil-loaded oral films.

Vuddanda PR , Montenegro-Nicolini M , Morales JO , Velaga S

Retrosynthesis of CaCO3 via amorphous precursor particles using gastroliths of the Red Claw lobster (Cherax quadricarinatus).

Neira-Carrillo A , Fernandez MS, Poblete Hevia G, Arias JL, Gebauer D, Colfen H

Reduced graphene oxides: Influence of the reduction method on the electrocatalytic effect towards nucleic acid oxidation

Baez DF , Pardo H, Laborda I, Marco JF, Yanez C, Bollo S

Metal nanoparticles for the treatment and diagnosis of neurodegenerative brain diseases.

Vio V , Marchant MJ , Araya E , Kogan MJ

The effects of gold nanoparticles functionalized with ß-amyloid specific peptides on an in vitro model of blood–brain barrier

Ruff J, Huwel S, Kogan MJ , Simon U , Galla HJ

Challenges and Future Prospects for the Delivery of Biologics: Oral Mucosal, Pulmonary, and Transdermal Routes

Morales JO , Fathe KR, Brunaugh A, Ferrati S, Li S, Montenegro-Nicolini M , Mousavikhamene Z, McConville JT , Prausnitz MR , Smyth HDC

Guias de Practica Clinica para el Tratamiento del Tabaquismo, Chile 2017.

Corvalan MP , Vejar L, Bambs C , Pavie J, Zagolin M, Cerda J. En representacion del Grupo Fenix

Infant morbidity and mortality attributable to prenatal smoking in Chile

Cerda J , Bambs C , Vera Perez-GC

High Exposure to Boron in Drinking Water and Sperm Parameters in Chilean Young People.

Cortes S , Espinoza-Navarro O , Ferreccio C

Association of Aflatoxin and Gallbladder Cancer.

Koshiol J , Gao Y-T, Dean M, Egner P, Nepal C, Jones K, Wang B, Rashid A, Luo W, Van Dyke AL, Ferreccio C , Malasky M, Shen M-C, Zhu B, Andersen JB, Hildesheim A, Hsing AQ, Groopman J

Associations between Arsenic (+3 Oxidation State) Methyltransferase (AS3MT) and N-6 Adenine-specific DNA Methyltransferase 1 (N6AMT1) Polymorphisms, Arsenic Metabolism, and Cancer Risk in a Chilean Population.

de la Rosa R, Steinmaus C, Akers NK, Conde L, Ferreccio C , Kalman D, Zhang KR, Skibola CF, Smith AH, Zhang L, Smith MT

Reply

Koshiol J , Andersen JB , Ferreccio C

Reprimo, a Potential p53-Dependent Tumor Suppressor Gene, Is Frequently Hypermethylated in Estrogen Receptor α-Positive Breast Cancer.

Buchegger K, Riquelme I, Viscarra T, Ili C, Brebi P, Huang TH, Roa JC

TNFα-Induced Mucin 4 Expression Elicits Trastuzumab Resistance in HER2-Positive Breast Cancer.

Mercogliano MF , De Martino M , Venturutti L, Rivas MA, Proietti CJ, Inurrigarro G, Frahm I, Allemand DH, Deza EG, Ares S, Gercovich FG, Guzman P, Roa JC , Elizalde PV, Schillaci R .

The ERK/MAPK pathway is overexpressed and activated in gallbladder cancer.

Buchegger K, Silva R, Lopez J, Ili C, Araya JC, Leal P, Brebi P, Riquelme I , Roa JC

Frequency of Human papillomavirus in women attending cervical cancer screening program in Chile

Brebi P , Ili CG, Andana A, Menzel D, Lopez J, Guzman P, Melo A , Buchegger K , Roa JC

Case-Control Study of Risk Factors for Meningococcal Disease in Chile.

Olea A , Matute I, Gonzalez C, Delgado I, Poffald L, Pedroni E, Alfaro T, Hirmas M, Najera M, Gormaz A, Lopez D, Loayza S, Ferreccio C , Gallegos D, Fuentes R, Vial P, Aguilera X.

High intraspecific variability of Echinococcus granulosus sensu stricto in Chile.

Alvarez Rojas CA , Ebi D, Paredes R, Acosta-Jamett G, Urriola N, Roa JC , Manterola C, Cortes S , Romig T, Scheerlinck JP, Lightowlers MW

The impact of BMI on non-malignant respiratory symptoms and lung function in arsenic exposed adults of Northern Chile

Nardone A, Ferreccio C, Acevedo J , Enanoria W, Blair A, Smith AH, Balmes J, Steinmaus C

Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile

Lorenzo Bermejo J , Boekstegers F , Gonzalez Silos R, Marcelain K, Baez Benavides P, Barahona Ponce C, Muller B, Ferreccio C , Koshiol J, Fischer C, Peil B, Sinsheimer J, Fuentes Guajardo M, Barajas O, Gonzalez-Jose R, Bedoya G, Catira Bortolini M, Canizales-Quinteros S, Gallo C, Ruiz Linares A, Rothhammer F

Precarious employment in Chile: psychometric properties of the Chilean version of Employment Precariousness Scale in private sector workers.

Vives-Vergara A , Gonzalez-Lopez F, Solar O, Bernales-Baksai P, Gonzalez MJ, Benach J

Changing the way we understand precarious employment and health: Precarisation affects the entire salaried population

Julia M , Vives A, Tarafa G, Benach J

Hypertension among adults exposed to drinking water arsenic in Northern Chile.

Hall EM , Acevedo J , Lopez FG, Cortes S, Ferreccio C, Smith AH, Steinmaus CM

Caveolin-1 expression increases upon maturation in dendritic cells and promotes their migration to lymph nodes thereby favoring the induction of CD8+ T cell responses

Oyarce, C., Cruz-Gomez, S., Galvez-Cancino, F., Vargas, P., Moreau, H., Diaz-Valdivia, N., Diaz, J., Salazar-Onfray, F., Pacheco, R., Lennon-Dumenil, A.M., Quest, A.F.G.* & Lladser, A.* .

Anti-neoplastic drugs increase caveolin-1-dependent migration, invasion and metastasis of cancer cells

Diaz-Valdivia NI, Calderon CC, Diaz JE, Lobos-Gonzalez L, Sepulveda H, Ortiz RJ, Martinez S, Silva V, Maldonado HJ, Silva P, Wehinger S, Burzio VA, Torres VA, Montecinos M, Leyton L, Quest AFG

Histatins, wound healing and cell migration.

Torres P, Castro M, Reyes M, Torres VA

Calpain2 mediates Rab5-driven focal adhesion disassembly and cell migration

Mendoza PA , Silva P, Diaz J, Arriagada C, Canales J, Cerda O, Torres VA

Role of Nerve Growth Factor (NGF) and miRNAs in Epithelial Ovarian Cancer

Retamales-Ortega R , Orostica L, Vera C, Cuevas P, Hernandez A, Hurtado I, Vega M, Romero C

The nerve growth factor alters calreticulin translocation from the endoplasmic reticulum to the cell surface and its signaling pathway in epithelial ovarian cancer cells.

Vera CA , Orostica L, Gabler F, Ferreira A, Selman A, Vega M,  Romero CA

αVβ3 Integrin regulates astrocyte reactivity.

Lagos-Cabre R , Alvarez A , Kong M, Burgos-Bravo F,  Cardenas A , Rojas-Mancilla E,  Perez-Nunez R , Herrera-Molina R, Rojas F, Schneider P, Herrera-Marschitz M,  Quest AFG , van Zundert B,  Leyton L

The Netrin-4/ Neogenin-1 axis promotes neuroblastoma cell survival and migration

Villanueva AA , Falcon P, Espinoza N, Milla L, Hernandez-San Miguel E,  Torres VA , Sanchez-Gomez P, Palma V

Helicobacter pylori Induced Phosphatidylinositol-3-OH Kinase/mTOR Activation Increases Hypoxia Inducible Factor-1a to Promote Loss of Cyclin D1 and G0/G1 Cell Cycle Arrest in Human Gastric Cells

Canales J , Valenzuela M, Bravo J, Cerda-Opazo P , Jorquera C , Toledo H, Bravo D , Quest, AFG

Angiogenesis inhibitors in early development for gastric cancer

Pinto M , Owen GI , Retamal I, Garrido M

The conundrum of the Epstein-Barr virus-associated gastric carcinoma in the Americas.

Carrasco-Avino G , Riquelme I, Padilla O, Villaseca M,  Aguayo FR, Corvalan AH

Upregulation of PIR gene expression induced by human papillomavirus E6 and E7 in epithelial oral and cervical cells.

Carrillo D , Munoz JP , Huerta H, Leal G,  Corvalan A , Leon O, Calaf GM, Urzua U, Boccardo E, Tapia JC,  Aguayo F

Reprimo tissue-specific expression pattern is conserved between zebrafish and human

Figueroa RJ ,  Carrasco-Avino G , Wichmann I A , Lange M,  Owen GI , Siekmann AF,  Corvalan AH , Opazo JC, Amigo JD

Expression of teneurins is associated with tumor differentiation and patient survival in ovarian cancer

Graumann R , Di Capua GA, Oyarzun JE, Vasquez MA, Liao C, Branes JA, Roa I, Casanello P,  Corvalan AH, Owen G I, Delgado I, Zangemeister-Wittke U, Ziegler A

Germline Mutations in PALB2, BRCA1, and RAD51C, Which Regulate DNA Recombination Repair, in Patients With Gastric Cancer

Sahasrabudhe R , Lott P, Bohorquez M, Toal T, Estrada AP, Suarez JJ, Brea-Fernandez A, Cameselle-Teijeiro J, Pinto C, Ramos I, Mantilla A, Prieto R,  Corvalan AH, Norero E , Alvarez C, Tapia T, Carvallo P, Gonzalez LM, Cock-Rada A, Solano A, Neffa F, Della Valle A, Yau C, Soares G, Borowsky A, Hu N, He LJ, Han XY; Latin American Gastric Cancer Genetics Collaborative Group, Taylor PR, Goldstein AM, Torres J, Echeverry M, Ruiz-Ponte C, Teixeira MR, Carvajal-Carmona LG .

Study protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014-2024

Ferreccio C , Roa JC, Bambs C, Vives A, Corvalan AH, Cortes S, Foerster C, Acevedo J, Huidobro A, Passi A, Toro P, Covacevich Y, de la Cruz R, Koshiol J, Olivares M, Miquel JF , Cruz F , Silva R , Quest AFG, Kogan MJ, Castro PF, Lavandero S

The case for aflatoxins in the causal chain of gallbladder cancer

Foerster C , Koshiol J , Guerrero AR, Kogan MJ, Ferreccio C

Gastric Cancer: Nanoparticles as Tools to Improve Treatment Efficacy

Guerrero AR , Oyarzun-Ampuero F, Hassan N, Corvalan AH, Quest AFG, Kogan MJ

miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway.

Riquelme I , Tapia O, Leal P, Sandoval A, Varga MG, Letelier P, Buchegger K , Bizama C , Espinoza JA, Peek RM, Araya JC, Roa JC

Basal autophagy protects cardiomyocytes from doxorubicin-induced toxicity.

Pizarro M, Troncoso R , Martinez GJ, Chiong M, Castro PF, Lavandero S .

Acute effect of iloprost inhalation on right atrial function and ventricular dyssynchrony in patients with pulmonary artery hypertension

Gabrielli L, Ocaranza MP , Sitges M, Kanacri A, Saavedra R, Sepulveda P, Sepulveda L, Rossel V, Zagolin M, Verdejo HE, Baraona F, Zalaquett R, Chiong M, Lavandero S, Castro PF

BAG3 regulates total MAP1LC3B protein levels through a translational but not transcriptional mechanism.

Rodriguez AE ,  Lopez-Crisosto C , Pena-Oyarzun D, Salas D,  Parra V, Quiroga C , Morawe T,  Chiong M , Behl C,  Lavandero S

HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1,4,5-trisphosphate receptor.

Paredes F ,  Parra V , Torrealba N, Navarro-Marquez M, Gatica D,  Bravo-Sagua R, Troncoso R, Pennanen C, Quiroga C, Chiong M , Caesar C, Taylor WR, Molgo J, San Martin A, Jaimovich E,  Lavandero S

New Molecular Insights of Insulin in Diabetic Cardiomyopathy

Westermeier F , Riquelme J, Pavez M , Garrido V, Diaz A, Verdejo H, Castro PF, Garcia L ,Lavandero S .

Heart Failure in rural Comunities

Verdejo H , Ferreccio C, Castro P

mTORC1 inhibitor rapamycin and ER stressor tunicamycin induce differential patterns of ERmitochondria coupling

Bravo-Sagua R , Lopez-Crisosto C, Parra V, Rodriguez-Pena M, Rothermel BA, Quest AF , Lavandero S.

Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells.

Rosas C , Orostica L, Poblete C, Carvajal R, Gabler F, Romero C , Lavandero S , Vega M .

Regulation of cardiomyocyte autophagy by calcium

Shaikh S , Troncoso R, Criollo A, Bravo-Sagua R , Garcia L , Morselli E, Cifuentes M, Quest AFG , Hill J, Lavandero S .

Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta.

Palacios J, Cifuentes F, Valderrama JA, Benites J, Rios D, Gonzalez C , Chiong M , Cartes-Saavedra B, Lafourcade C, Wyneken U, Gonzalez P, Owen GI , Pardo F, Sobrevia L, Buc Calderon P.